Evidence map›Paper›PMID 32668180›Full record

ArticleJournal of adolescent and young adult oncology2020

Hypogammaglobulinemia in Adolescents and Young Adults with Acute Lymphoblastic Leukemia.

Cassandra S Lange, April Rahrig, Sandra K Althouse, Robert P Nelson, Sandeep Batra

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of adolescent and young adult oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Role of Hypogammaglobulinemia in Invasive Fungal Infections in Children May Be OverlookedTurkish journal of haematology : official journal of Turkish Society of Haematology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Cassandra S LangeIndiana University School of Medicine, Indianapolis, Indiana, USA.
April RahrigIndiana University School of Medicine, Indianapolis, Indiana, USA.
Sandra K AlthouseDepartment of Biostatistics and Indiana University School of Medicine, Indianapolis, Indiana, USA.
Robert P NelsonDepartment of Pediatric Hematology and Oncology, Riley Hospital for Children, Indianapolis, Indiana, USA.
Sandeep BatraDepartment of Pediatric Hematology and Oncology, Riley Hospital for Children, Indianapolis, Indiana, USA.
Riley Hospital for Children · USIndiana University Health · USIndiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Short-Term Training Program In Biomedical SciencesT35HL110854 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Brittney-Shea Herbert, Catherine Rufatto Sears · 2012 to 2026
$3.4M
6 · The paper itself

Abstract

Hypogammaglobulinemia is a poorly described complication of chemotherapy in adolescents and young adults (AYAs, 15-39 years) with acute lymphoblastic leukemia (ALL). The majority of AYAs treated on a Berlin-Frankfurt-Munster-based ALL regimen experienced hypogammaglobulinemia (65.0% [13/20]). Febrile neutropenia episodes (throughout the treatment course) and infectious events during maintenance occurred more frequently in hypogammaglobulinemic patients compared with patients with normal immunoglobulin G levels (

Indexed as

AdolescentAdultAgammaglobulinemiaFemaleHumansMalePrecursor Cell Lymphoblastic Leukemia-LymphomaYoung Adulthypogammaglobulinemialeukemiapediatricside effects

Identifiers

PMID32668180
PMCPMC7757595
OpenAlexW3042892228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.