Evidence map›Paper›PMID 32668165›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2020

SARS-CoV-2 (COVID-19) and cystic fibrosis.

Bruce A Stanton, Thomas H Hampton, Alix Ashare

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04904445 (COVID-19 Antibody Responses In Cystic Fibrosis), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04904445 completednot on this mapstarted 2021, after this paper: background citation

COVID-19 Antibody Responses In Cystic Fibrosis

TypeobservationalSponsorErasmus Medical CenterRan2021 to 2024Enrolled40ConditionsCystic Fibrosis
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Genetic and chemical correction of cystic fibrosis reduces airway susceptibility to SARS-CoV-2.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  14. Article
  15. Article
  16. COVID-19 in Patients with Chronic Lung Disease.Clinics in chest medicine · 2023
    Review
  17. Respiratory Care in Children with COVID-19.Journal of pediatric intensive care · 2023
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bruce A StantonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Thomas H HamptonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.ORCID 0000-0003-0543-402X
Alix AshareDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Dartmouth College · US

Funding

Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Role of Virulence Factors in Pseudomonas-Host InteractionsR01HL074175 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2003 to 2018
$5.0M
Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung InfectionsR01HL151385 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2021 to 2024
$2.4M
Regional Hypoxia Impacts the Heterogeneity of Inflammatory Lung DiseaseR01HL122372 · NHLBI · DARTMOUTH-HITCHCOCK CLINIC · PI ASHARE, ALIX · 2015 to 2019
$2.0M
NHLBI NIH HHS R01 HL074175NHLBI NIH HHS R01 HL122372NHLBI NIH HHS R01 HL151385NIDDK NIH HHS P30 DK117469
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a genetic disease caused by mutations in the

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19Cystic FibrosisEpithelial CellsHumansInflammationLungPandemicsPeptidyl-Dipeptidase APneumonia, ViralSARS-CoV-2Peptidyl-Dipeptidase AACE2COVID-19cystic fibrosisSARS-CoV-2TMPRSS2

Identifiers

PMID32668165
PMCPMC7518058
OpenAlexW3043080855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.