Evidence map›Paper›PMID 32668037›Full record

ReviewNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2020

Gastrointestinal Manifestations of COVID-19: Impact on Nutrition Practices.

Enrik John T Aguila, Ian Homer Y Cua, Joy Arabelle C Fontanilla, Vince Leenard M Yabut, Marion Frances P Causing

Abstract readReview
In one paragraph

Review in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Review
  6. Article
  7. Article
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  9. Article
  10. COVID, the Gut, and Nutritional Implications.Current surgery reports · 2023
    Review
  11. Article
  12. Review
  13. Review
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  15. The COVID-19 Patient in the Surgical Intensive Care Unit.The Surgical clinics of North America · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Gastrointestinal manifestations in COVID-19.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Enrik John T AguilaInstitute of Digestive and Liver Diseases, St Luke's Medical Center Global City, Taguig City, Metro Manila, Philippines.ORCID https://orcid.org/0000-0003-3440-2406
Ian Homer Y CuaInstitute of Digestive and Liver Diseases, St Luke's Medical Center Global City, Taguig City, Metro Manila, Philippines.
Joy Arabelle C FontanillaCenter for Weight Intervention and Nutrition Services, St Luke's Medical Center Global City, Taguig City, Metro Manila, Philippines.
Vince Leenard M YabutClinical Nutrition Service, St Luke's Medical Center Quezon City, Metro Manila, Philippines.
Marion Frances P CausingDepartment of Pediatrics, The Medical City, Pasig City, Metro Manila, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although Coronavirus disease 2019 (COVID-19) is primarily a respiratory disease, growing evidence shows that it can affect the digestive system and present with gastrointestinal (GI) symptoms. Various nutrition societies have recently published their guidelines in context of the pandemic, and several points emphasize the impact of these GI manifestations on nutrition therapy. In patients with COVID-19, the normal intestinal mucosa can be disrupted by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, and this could result in GI symptoms and a compromise in nutrient absorption. Optimization of oral diet is still recommended. However, given the GI effects of COVID-19, a fraction of infected patients have poor appetite and would not be able to meet their nutrition goals with oral diet alone. For this at-risk group, which includes those who are critically ill, enteral nutrition is the preferred route to promote gut integrity and immune function. In carrying this out, nutrition support practices have been revised in such ways to mitigate viral transmission and adapt to the pandemic. All measures in the GI and nutrition care of patients are clustered to limit exposure of healthcare workers. Among patients admitted to intensive care units, a significant barrier is GI intolerance, and it appears to be exacerbated by significant GI involvement specific to the SARS-CoV-2 infection. Nevertheless, several countermeasures can be used to ease side effects. At the end of the spectrum in which intolerance persists, the threshold for switching to parenteral nutrition may need to be lowered.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19Critical CareGastrointestinal DiseasesGastrointestinal TractHumansNutritional SupportPandemicsPneumonia, ViralSARS-CoV-2COVID-19digestive systementeral nutritiongastrointestinal symptomsgastrointestinal tractnutrition supportparenteral nutritionSARS-CoV-2

Identifiers

PMID32668037
PMCPMC7405319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.