Evidence map›Paper›PMID 32667526›Full record

ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2020

BRAZILIAN CONSENSUS ON INCIDENTAL GALLBLADDER CARCINOMA.

Grupo Internacional de Estudos de Câncer Hepatopancreatobiliar - ISG-HPB-Cancer, Felipe Jose F Coimbra, Orlando Jorge M Torres, Ruslan Alikhanov, Anil Agarwal, Patrick Pessaux, Eduardo de Souza M Fernandes, Claudemiro Quireze-Junior, Raphael Leonardo C Araujo, André Luis Godoy and 28 more

Abstract readConsensus Statement
In one paragraph

Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. ASYMPTOMATIC CHOLELITHIASIS: EXPECTANT OR CHOLECYSTECTOMY. A SYSTEMATIC REVIEW.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. A POPULATION STUDY ON GENDER AND ETHNICITY DIFFERENCES IN GALLBLADDER DISEASE IN BRAZIL.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
  8. Approach to Resectable Biliary Cancers.Current treatment options in oncology · 2021
    Review
  9. Article
  10. IS THERE A CLINICAL PATHOLOGICAL CORRELATION OF COLORECTAL ADENOCARCINOMA WITH THE IMMUNOHISTOCHEMICAL EXPRESSION OF OPN AND ABCB5?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021
    Article
  11. WHAT'S NEW IN INFECTION ON SURGICAL SITE AND ANTIBIOTICOPROPHYLAXIS IN SURGERY?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Grupo Internacional de Estudos de Câncer Hepatopancreatobiliar - ISG-HPB-Cancer
Felipe Jose F CoimbraDepartment of Gastrointestinal Surgery, AC Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-5068-0639
Orlando Jorge M TorresDepartment of Hepatopancreatobiliary Surgery, Federal University of Maranhão, São Luis, Brazil.ORCID http://orcid.org/0000-0002-7398-5395
Ruslan AlikhanovDepartment of Hepatopancreatobiliary Surgery, Moscow Clinical Scientific Center, Moscow, Russia.ORCID http://orcid.org/0000-0002-8602-514X
Anil AgarwalDepartment of Gastrointestinal Surgery, Govind Ballabh Pant Hospital, New Delhi, India.ORCID http://orcid.org/0000-0003-1154-1526
Patrick PessauxDepartment of Hepatopancreatobiliary Surgery, Nouvel Hopital Civil, University Hospital of Strasbourg, Strasbourg, France.ORCID http://orcid.org/0000-0001-5635-7437
Eduardo de Souza M FernandesDepartment of Hepatopancreatobiliary and Transplant Surgery, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0003-1304-5075
Claudemiro Quireze-JuniorDepartment of Gastrointestinal Surgery, Federal University of Goiás, Goiânia, Brazil.ORCID http://orcid.org/0000-0002-5569-5052
Raphael Leonardo C AraujoDepartment of Hepatobiliary Surgery, Federal University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7834-5944
André Luis GodoyDepartment of Gastrointestinal Surgery, AC Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7154-1184
Fabio Luis WaechterDepartment of Gastrointestinal Surgery, Santa Casa de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0003-3020-0102
Alexandre Prado de ResendeDepartment of General Surgery, Mater Dei Hospital, Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0003-0113-0707
Marcio Fernando BoffDepartment of Oncology Surgery, Mãe de Deus Hospital, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0003-2790-079X
Gustavo Rego CoelhoDepartment of Hepatopancreatobiliary Surgery, Hospital Walter Cantidio, Fortaleza, Brazil.ORCID http://orcid.org/0000-0003-0845-2864
Marcelo Bruno de RezendeDepartment of Hepatopancreatobiliary Surgery, Hospital Albert Einstein, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-8417-4985
Marcelo Moura LinharesDepartment of Hepatobiliary Surgery, Federal University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9540-5937
Marcos BelottoDepartment of Gastrointestinal Surgery, Santa Casa de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-5630-5004
Jose Maria A Moraes-JuniorDepartment of Hepatopancreatobiliary Surgery, Federal University of Maranhão, São Luis, Brazil.ORCID http://orcid.org/0000-0001-5087-1873
Paulo Cezar G AmaralDepartment of Gastrointestinal Surgery, Hospital São Rafael, Salvador, Brazil.ORCID http://orcid.org/0000-0002-2510-0193
Rinaldo Danesi PintoDepartment of Gastrointestinal Surgery, Hospital Santa Catarina, Blumenal, Brazil.ORCID http://orcid.org/0000-0003-4847-6676
Tercio GenziniDepartment of Hepatopancreatobiliary Surgery, Hospital Beneficiência Portuguesa, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-3589-3983
Agnaldo Soares LimaDepartment of Hepatopancreatobiliary Surgery, Santa Casa de Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0001-6421-3062
Heber Salvador C RibeiroDepartment of Gastrointestinal Surgery, AC Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-3412-7451
Eduardo José RamosDepartment of Hepatopancreatobiliary Surgery, Hospital NS das Graças, Curitiba, Brazil.ORCID http://orcid.org/0000-0002-7151-9956
Marciano AnghinoniDepartment of Oncology Surgery, Hospital São Vicente, Curitiba, Brazil.ORCID http://orcid.org/0000-0001-9501-2650
Lucio Lucas PereiraDepartment of Gastrointestinal Surgery, Hospital Sírio-Libanês, Brasilia, Brazil.ORCID http://orcid.org/0000-0002-8094-5316
Marcelo EnneDepartment of Hepatopancreatobiliary Surgery, Ipanema Hospital, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-8714-3295
Adriano SampaioDepartment of Gastrointestinal Surgery, Santo Amaro University, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0417-3035
André Luis MontagniniDepartment of Hepatopancreatobiliary Surgery, São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9575-9196
Alessandro DinizDepartment of Gastrointestinal Surgery, AC Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9671-2026
Victor Hugo Fonseca de JesusDepartment of Gastrointestinal Oncology, AC Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-4702-116X
Bhawna SirohiDepartment of Hepatopancreatobiliary and Oncology Surgery, Tata Memorial Hospital, Mumbai, India.ORCID http://orcid.org/0000-0001-8093-1531
Shailesh V ShrikhandeDepartment of Hepatopancreatobiliary and Oncology Surgery, Tata Memorial Hospital, Mumbai, India.ORCID http://orcid.org/0000-0002-8036-4212
Renata D Alpino PeixotoDepartment of Gastrointestinal Oncology, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0053-7951
Antonio Nocchi KalilDepartment of Gastrointestinal Oncology, Santa Casa de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-2658-0731
Nicolas JarufeDepartment of Hepatopancreatobiliary Surgery, Universidade Católica, Santiago, Chile.ORCID http://orcid.org/0000-0002-7134-0307
Martin SmithDepartment of Hepatopancreatobiliary Surgery, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa.ORCID http://orcid.org/0000-0003-3470-7576
Paulo HermanDepartment of Hepatopancreatobiliary Surgery, São Paulo Medical School, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-2859-5846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncidental gallbladder cancer is defined as a cancer discovered by histological examination after cholecystectomy. It is a potentially curable disease. However, some questions related to their management remain controversial and a defined strategy is associated with better prognosis.

aimTo develop the first evidence-based consensus for management of patients with incidental gallbladder cancer in Brazil.

methodsSixteen questions were selected, and 36 Brazilian and International members were included to the answer them. The statements were based on current evident literature. The final report was sent to the members of the panel for agreement assessment.

resultsIntraoperative evaluation of the specimen, use of retrieval bags and routine histopathology is recommended. Complete preoperative evaluation is necessary and the reoperation should be performed once final staging is available. Evaluation of the cystic duct margin and routine 16b1 lymph node biopsy is recommended. Chemotherapy should be considered and chemoradiation therapy if microscopically positive surgical margins. Port site should be resected exceptionally. Staging laparoscopy before reoperation is recommended, but minimally invasive radical approach only in specialized minimally invasive hepatopancreatobiliary centers. The extent of liver resection is acceptable if R0 resection is achieved. Standard lymph node dissection is required for T2 tumors and above, but common bile duct resection is not recommended routinely.

conclusionsIt was possible to prepare safe recommendations as guidance for incidental gallbladder carcinoma, addressing the most frequent topics of everyday work of digestive and general surgeons.

Indexed as

Gallbladder NeoplasmsBrazilCarcinomaFemaleHumansIncidental FindingsLymph Node ExcisionNeoplasm StagingPositron Emission Tomography Computed TomographyRetrospective Studies

Identifiers

PMID32667526
PMCPMC7357549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.