Evidence map›Paper›PMID 32667261›Full record

Observational studyAmerican journal of respiratory and critical care medicine2021

Urinary Leukotriene E

Johan Kolmert, Cristina Gómez, David Balgoma, Marcus Sjödin, Johan Bood, Jon R Konradsen, Magnus Ericsson, John-Olof Thörngren, Anna James, Maria Mikus and 30 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Skin-lung axis in the atopic march: The immune link from skin to lungs.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prostaglandin Metabolites Analysis in Urine by LC-MS/MS.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  16. Article
  17. Neutrophils in Atopic Dermatitis.Clinical reviews in allergy & immunology · 2024
    Review
  18. Article
  19. Urinary eicosanoid levels in early life and risk of atopic disease in childhood.The Journal of allergy and clinical immunology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

40 authors at 20 institutions in 17 countries.

Johan KolmertThe Institute of Environmental Medicine.ORCID 0000-0001-7116-6583
Cristina GómezThe Institute of Environmental Medicine.
David BalgomaThe Institute of Environmental Medicine.
Marcus SjödinThe Institute of Environmental Medicine.
Johan BoodThe Institute of Environmental Medicine.
Jon R KonradsenThe Center for Allergy Research.
Magnus EricssonDepartment of Clinical Pharmacology, Huddinge Campus, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
John-Olof ThörngrenDepartment of Clinical Pharmacology, Huddinge Campus, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Anna JamesThe Institute of Environmental Medicine.
Maria MikusThe Institute of Environmental Medicine.ORCID 0000-0001-6560-6124
Ana R SousaAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
John H RileyAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Stewart BatesAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Per S BakkeGlaxoSmithKline, London, United Kingdom.
Ioannis PandisInstitute of Medicine, University of Bergen, Bergen, Norway.
Massimo CarusoNational Heart and Lung Institute and Department of Computing & Data Science Institute, Imperial College London, London, United Kingdom.
Pascal ChanezDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Stephen J FowlerClinique des Bronches, Allergies et Sommeil, Aix Marseille Université, Assistance Publique des Hôpitaux de Marseille, Marseille, France.
Thomas GeiserDivision of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, and Manchester Academic Health Science Centre and National Institute for Health Research Biomedical Research Centre, Manchester University Hospitals National Health Service Foundation Trust, Manchester, United Kingdom.
Peter HowarthDepartment of Pulmonary Medicine, University Hospital Bern, Bern, Switzerland.
Ildikó HorváthFaculty of Medicine, Southampton University, and National Institute for Health Research Southampton Respiratory Biomedical Research Center, University Hospital Southampton, Southampton, United Kingdom.
Norbert KrugDepartment of Pulmonology, Semmelweis University, Budapest, Hungary.
Paolo MontuschiFraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
Marek SanakDepartment of Pharmacology, Catholic University of the Sacred Heart, and Agostino Gemelli University Hospital Foundation, IRCCS, Rome, Italy.
Annelie BehndigDepartment of Internal Medicine, Medical College, Jagiellonian University, Cracow, Poland.
Dominick E ShawDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Richard G KnowlesNottingham National Institute for Health Research Biomedical Research Centre, University of Nottingham, United Kingdom.
Cécile T J HolwegKnowles Consulting, Stevenage Bioscience Catalyst, Stevenage, United Kingdom.
Åsa M WheelockGenentech Inc., South San Fransisco, California.ORCID 0000-0002-8013-2745
Barbro DahlénThe Center for Allergy Research.
Björn NordlundRespiratory Medicine Unit, Department of Medicine, Solna Campus, and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Kjell AlvingDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden; and.
Gunilla HedlinThe Center for Allergy Research.
Kian Fan ChungInstitute of Medicine, University of Bergen, Bergen, Norway.
Ian M AdcockInstitute of Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-2101-8843
Peter J SterkDepartment of Respiratory Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Ratko DjukanovicDepartment of Pulmonary Medicine, University Hospital Bern, Bern, Switzerland.
Sven-Erik DahlénThe Institute of Environmental Medicine.ORCID 0000-0002-4993-4002
Craig E WheelockDivision of Physiological Chemistry II, Department of Medical Biochemistry and Biophysics.ORCID 0000-0002-8113-0653
U-BIOPRED Study Group, on behalf of the U-BIOPRED Study Group
Karolinska Institutet · SEKarolinska University Hospital · SELung Institute · USUniversity Hospital of Bern · CHUniversity of Catania · ITAgostino Gemelli University Polyclinic · ITAix-Marseille Université · FRCisco Systems (China) · CNENT and Allergy · USGlaxoSmithKline (United Kingdom) · GBInstitute of Molecular Medicine · INJagiellonian University · PLNational Health Service · GBSemmelweis University · HUUmeå University · SEUniversità Cattolica del Sacro Cuore · ITUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Amsterdam · NLUniversity of Nottingham · GBUppsala University · SE

Funding

Medical Research Council MR/N005953/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAsthmaBiomarkersFemaleHumansInflammationLeukotriene E4MaleMiddle AgedProstaglandinsBiomarkersLeukotriene E4Prostaglandinsmass spectrometrysevere asthmatype 2 inflammationU-BIOPREDurinary eicosanoid metabolites

Identifiers

PMID32667261
PMCPMC7781128
OpenAlexW3043389322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.