ArticleThe EMBO journal2020
Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage.
Article in The EMBO journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Diet and microbiome shape small-molecule cytokinin pools in mammals.Gut microbes · 2026Article
- Tyrosine-sulfated peptide-induced flavonol biosynthesis controls elongation and differentiation in Arabidopsis primary root.The Plant cell · 2026Article
- Hormonal regulation of root growth under moderately elevated temperatures.Annals of botany · 2025Review
- Cytokinin-responsive P-type cyclins control Arabidopsis radial style morphology.The Plant journal : for cell and molecular biology · 2025Article
- A FLOE-related protein regulates the two-dimensional to three-dimensional growth transition in the moss Physcomitrium patens.Development (Cambridge, England) · 2025Article
- Convergent evolution of plant prickles by repeated gene co-option over deep time.Science (New York, N.Y.) · 2024Article
- Microtubule-associated protein SlMAP70 interacts with IQ67-domain protein SlIQD21a to regulate fruit shape in tomato.The Plant cell · 2023Article
- Article
- Imaging the living plant cell: From probes to quantification.The Plant cell · 2022Review
- Mitogen-Activated Protein Kinase 4-Regulated Metabolic Networks.International journal of molecular sciences · 2022Article
- The root apoplastic pH as an integrator of plant signaling.Frontiers in plant science · 2022Review
- Article
- Integrative Roles of Phytohormones on Cell Proliferation, Elongation and Differentiation in theFrontiers in plant science · 2021Review
- Dynamic cytokinin signalling landscapes during lateral root formation in Arabidopsis.Quantitative plant biology · 2021Review
- GR24, A Synthetic Strigolactone Analog, and Light Affect the Organization of Cortical Microtubules in Arabidopsis Hypocotyl Cells.Frontiers in plant science · 2021Article
- Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage.The EMBO journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
Cell production and differentiation for the acquisition of specific functions are key features of living systems. The dynamic network of cellular microtubules provides the necessary platform to accommodate processes associated with the transition of cells through the individual phases of cytogenesis. Here, we show that the plant hormone cytokinin fine-tunes the activity of the microtubular cytoskeleton during cell differentiation and counteracts microtubular rearrangements driven by the hormone auxin. The endogenous upward gradient of cytokinin activity along the longitudinal growth axis in Arabidopsis thaliana roots correlates with robust rearrangements of the microtubule cytoskeleton in epidermal cells progressing from the proliferative to the differentiation stage. Controlled increases in cytokinin activity result in premature re-organization of the microtubule network from transversal to an oblique disposition in cells prior to their differentiation, whereas attenuated hormone perception delays cytoskeleton conversion into a configuration typical for differentiated cells. Intriguingly, cytokinin can interfere with microtubules also in animal cells, such as leukocytes, suggesting that a cytokinin-sensitive control pathway for the microtubular cytoskeleton may be at least partially conserved between plant and animal cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.