ArticleThe neuroradiology journal2020
Obesity and pituitary gland volume - a correlation study using three-dimensional magnetic resonance imaging.
Article in The neuroradiology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Neuroimaging Investigations of Obesity: a Review of the Treatment of Sex from 2010.Current obesity reports · 2023Pooled it
- Identification and characterization of the long non-coding RNA NFIA-AS2 as a novel locus for body mass index in American Indians.International journal of obesity (2005) · 2023Pooled it
- Cranial MRI in Girls With Central Precocious Puberty: Clinical Characteristics and Predictors of Abnormal Findings.Saudi medical journal · 2026Article
- Pituitary Gland Volume in Fibromyalgia Syndrome: A Case-Control Volumetric MRI Study.Journal of pain research · 2026Article
- Correlation of 3D MRI-Derived Adenohypophysis Volume With Height and Peak GH in Peripubertal Children.Brain and behavior · 2025Article
- Morphometric study of the pituitary gland and stalk with emphasis on lifestyle factors.Pituitary · 2025Article
- Neuroanatomical Reflections of Childhood Obesity: Volumetric Analysis of the Pituitary Gland and Olfactory Bulb.Children (Basel, Switzerland) · 2025Article
- Assessing the Diagnostic Performance of Automated Pituitary Gland Volume Measurement for Idiopathic Central Precocious Puberty.Journal of clinical medicine · 2024Article
- Structure-function relationship of the pituitary gland in anorexia nervosa and intense physical activity.Brain structure & function · 2024Article
- deepPGSegNet: MRI-based pituitary gland segmentation using deep learning.Frontiers in endocrinology · 2024Article
- Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study.International journal of obesity (2005) · 2023Review
- Article
- Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeObesity has become a major health problem and is associated with endocrine disorders and a disturbed hypothalamic-pituitary axis. The purpose of this study was to correlate pituitary gland volume determined by routine magnetic resonance imaging with patient characteristics, in particular body mass index and obesity. MATERIAL AND
methodsA total of 144 'healthy' patients with normal findings in cerebral magnetic resonance imaging were retrospectively included. Pituitary gland volume was measured in postcontrast three-dimensional T1-weighted sequences. A polygonal three-dimensional region of interest covering the whole pituitary gland was assessed manually. Physical characteristics (gender, age, body height and body mass index) were correlated with pituitary gland volume. Multiple subgroup and regression analyses were performed.
resultsPituitary gland volumes were significantly larger in females than in males (
conclusionPituitary gland volume is increased in obese individuals and a high body mass index can be seen as an independent predictor of increased pituitary gland volume. Therefore, gland enlargement might be an imaging indicator of dysfunction in the hypothalamus-pituitary axis. Besides gender and age, body mass index should be considered by radiologists when diagnosing abnormal changes in pituitary gland volume.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.