ArticleBrain and behavior2020
Differences in the amplitude of low-frequency fluctuation between methamphetamine and heroin use disorder individuals: A resting-state fMRI study.
Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The resting-state brain activity signatures for addictive disorders.Med (New York, N.Y.) · 2024Pooled it
- Morphological Brain Alterations and Network Disorganizations in Individuals With Substance Use Disorders: Differential Effects of Heroin Versus Methamphetamine.Brain and behavior · 2025Article
- Functional brain network identification in opioid use disorder using machine learning analysis of resting-state fMRI BOLD signals.Computers in biology and medicine · 2025Article
- A brainnetome atlas-based methamphetamine dependence identification using neighborhood component analysis and machine learning on functional MRI data.Frontiers in cellular neuroscience · 2022Article
- Changes in ALFF and ReHo values in methamphetamine abstinent individuals based on the Harvard-Oxford atlas: A longitudinal resting-state fMRI study.Addiction biology · 2022Article
- The potency of psychiatric questionnaires to distinguish major mental disorders in Chinese outpatients.Frontiers in psychiatry · 2022Article
- Regional Homogeneity Abnormalities and Its Correlation With Impulsivity in Male Abstinent Methamphetamine Dependent Individuals.Frontiers in molecular neuroscience · 2021Article
- Identification of Methamphetamine Abstainers by Resting-State Functional Magnetic Resonance Imaging.Frontiers in psychology · 2021Article
- Differences in the amplitude of low-frequency fluctuation between methamphetamine and heroin use disorder individuals: A resting-state fMRI study.Brain and behavior · 2020Article
- Resting-state fMRI in women with functional constipation with or without stress urinary incontinence.Frontiers in neurologyArticle
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
introductionMethamphetamine has surpassed heroin as the most popular abused drug in China. Although the use of both heroin and methamphetamine leads to use disorders through dysfunction of the dopamine pathway, the incidence of psychiatric disorder caused by methamphetamine abuse is higher than the incidence of psychiatric disorder caused by heroin abuse. The difference in resting-state function between heroin use disorder (HUD) and methamphetamine use disorder (MAUD) and the relationship between resting-state function and psychiatric disorder related to MAUD are unknown.
methodsIn the present study, 21 male individuals with MAUD, 21 demographically matched individuals with HUD, and 21 normal controls (NC) were recruited. The amplitude of low-frequency fluctuation (ALFF) during resting-state brain function was measured by magnetic resonance imaging. Psychiatric status was evaluated by the Symptom Checklist-90 (SCL90).
resultsIndividuals with MAUD had increased SCL90 scores compared to those of the NC for anxiety, paranoia, and additional items, and the hostility score was significantly increased compared to that of individuals with HUD. There is no significant difference between HUD and NC individuals. Individuals with MAUD had increased ALFF compared to those of the NC for thalamus, right postcentral, and right inferior temporal gyri, but a decreased ALFF in the cerebellum. Individuals with HUD had significantly increased ALFF compared to those of the NC for left middle frontal gyrus but a decreased ALFF in the left postcentral gyrus. Individuals with MAUD had significantly increased ALFF compared to those of the HUD for thalamus, the right inferior temporal, and bilateral postcentral gyri, and the ALFF of cerebellum and left middle frontal was significantly increased.
conclusionsMethamphetamine can induce more serious psychiatric disorders than heroin. The resting-state function involved in mood adjustment, the auditory, and memory-related brain regions may affect psychotic symptoms related to MAUD.
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