ArticleTransplant infectious disease : an official journal of the Transplantation Society2021
COVID-19, liver transplant, and immunosuppression: Allies or foes?
Article in Transplant infectious disease : an official journal of the Transplantation Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- The Impact and Evolution of COVID-19 on Liver Transplant Recipients Throughout the Pandemic "Waves" in a Single Center.Viruses · 2025Observational
- Outcomes of COVID-19 in 24 hospitalized liver transplant recipients: an observational study.BMC infectious diseases · 2024Observational
- The Italian data on SARS-CoV-2 infection in transplanted patients support an organ specific immune response in liver recipients.Frontiers in immunology · 2023Article
- COVID-19 infection frequency and clinical course in patients with liver transplantation: Results of a single transplant center in Türkiye.Turkish journal of surgery · 2022Article
- Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units.World journal of hepatology · 2021Review
- SARS-CoV-2 Seroprevalence and Clinical Features of COVID-19 in a German Liver Transplant Recipient Cohort: A Prospective Serosurvey Study.Transplantation proceedings · 2021Article
- The hamletic dilemma of patients waiting for kidney transplantation during the COVID-19 pandemic: To accept or not to accept (an organ offer)?Transplant infectious disease : an official journal of the Transplantation Society · 2021Article
- COVID-19, liver transplant, and immunosuppression: Allies or foes?Transplant infectious disease : an official journal of the Transplantation Society · 2021Article
- Recovery of Moderate Coronavirus Disease 2019 in a Liver Transplant Recipient on Continued Immunosuppression: A Case Report.Transplantation proceedings · 2020Article
- SARS-COV-2 positive donors for liver transplantation - the way forward.Journal of liver transplantationArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver transplant (LT) recipients are considered at a particularly high risk for developing critical COVID-19 infection. To date, available data are heterogeneous and scarce and mortality in LT recipients seems to be higher compared to normal population, but whether this is caused by altered immunological status, immunosuppression (IS), or underlying comorbidities has not yet been fully clarified. Some evidences show that IS might play a role in the pathophysiology of this new disease. We searched all available data regarding LT recipients infected by COVID-19, focusing on the role of IS. To date, 244 LT recipients have been reported as COVID-19-positive. Trends among transplant physicians are to reduce overall IS, especially antimetabolite drugs, but the current available observations are still not enough to build strong evidences for recommendation and IS should be meticulously tailored case by case.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.