Evidence map›Paper›PMID 32666479›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

Leprosy surveillance study in a highly endemic Brazilian area using leprosy specific serologic tests and IFNγ whole blood assay.

Aline do Carmo Gonçalves, Emerith Mayra Hungria, Aline Araújo Freitas, Samira Sékula-Bührer, Cassia Maria Gomes, Ana Cecília Coelho, Laura Branquinho Nascimento, Mariane Martins de Araújo Stefani

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Challenges and advances in serological and molecular tests to aid leprosy diagnosis.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Aline do Carmo GonçalvesTropical Pathology and Public Health Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Emerith Mayra HungriaTropical Pathology and Public Health Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Aline Araújo FreitasTropical Pathology and Public Health Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Samira Sékula-BührerTropical Pathology and Public Health Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Cassia Maria GomesHospital de Doenças Tropicais Anuar Auad, Goiânia, Goiás, Brazil.
Ana Cecília CoelhoSuperintendência de Vigilância em Saúde, Secretaria Municipal de Saúde de Goiânia, Goiânia, Goiás, Brazil.
Laura Branquinho NascimentoSuperintendência de Vigilância em Saúde, Secretaria Municipal de Saúde de Goiânia, Goiânia, Goiás, Brazil.
Mariane Martins de Araújo StefaniTropical Pathology and Public Health Institute, Federal University of Goiás, Goiânia, Goiás, Brazil. mmastefani@gmail.com.ORCID http://orcid.org/0000-0001-7874-4315
Universidade Federal de Goiás · BRSecretaria da Saúde · BRFundação de Apoio a Pesquisa do Estado de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This surveillance study evaluated leprosy-serologic tests and the IFNγ whole-blood-assay/WBA as adjunct diagnostic tools. Previously diagnosed leprosy index cases, intradomiciliary, peridomiciliary contacts from a Brazilian endemic area were enrolled during domiciliary visits. Physical evaluation was performed by trained nurses and leprosy diagnosis confirmed by expert dermatologist. ELISA detected IgM anti-PGL-I, IgG anti-LID-1, and IgM/IgG anti-ND-O-LID antibodies. Heparinized WBA plasma stimulated with LID-1, 46f + LID-1, ML0276 + LID-1 (24 h, 37 °C, 5% CO

Indexed as

AdolescentAdultAntibodies, BacterialAntigens, BacterialBrazilFemaleHumansInterferon-gammaInterferon-gamma Release TestsLeprosyMaleMiddle AgedMycobacterium lepraeROC CurveSerologic TestsYoung AdultAntibodies, BacterialAntigens, BacterialInterferon-gammaIFNγ-whole-blood-assayLeprosy surveyLID-1ND-O-LIDPGL-ISerology

Identifiers

PMID32666479
OpenAlexW3043096364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.