Evidence map›Paper›PMID 32666427›Full record

ArticleJournal of thrombosis and thrombolysis2021

Patient-guided modifications of oral anticoagulant drug intake during Ramadan fasting: a multicenter cross-sectional study.

AbdulAziz Batarfi, Haitham Alenezi, Abdulrahman Alshehri, Saud Balelah, Hameedullah Kazim, Mohammed Algthami, Mariam M Hussain, Nada Alshehri, Rahaf Alsharif, Hadeel Ashour and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

AbdulAziz BatarfiDepartment of Neurology, University Hospital of Frankfurt, Goethe-University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany. Abdulaziz.batarfi@kgu.de.ORCID http://orcid.org/0000-0003-4184-507X
Haitham AleneziDepartment of Cardiology, King AbdulAziz Medical City Complex, Riyadh, Saudi Arabia.
Abdulrahman AlshehriDepartment of Internal Medicine, Aseer Central Hospital, Abha, Saudi Arabia.
Saud BalelahDepartment of Internal Medicine, King Fahad General Hospital, Madinah, Saudi Arabia.
Hameedullah KazimDepartment of Cardiology, Al Hada Armed Forces Hospital, Taif, Saudi Arabia.
Mohammed AlgthamiDepartment of Internal Medicine, Al Hada Armed Forces Hospital, Taif, Saudi Arabia.
Mariam M HussainCollege of Medicine, King Saud Bin AbdulAziz University, Riyadh, Saudi Arabia.
Nada AlshehriCollege of Medicine, King Khaled University, Abha, Saudi Arabia.
Rahaf AlsharifCollege of Medicine, Taibah University, Madinah, Saudi Arabia.
Hadeel AshourCollege of Medicine, Taif University, Taif, Saudi Arabia.
Mutaz AlthobaitiCollege of Medicine, Taif University, Taif, Saudi Arabia.
Shomokh AlotaibiCollege of Medicine, King AbdulAziz University, Jeddah, Saudi Arabia.
Helmuth SteinmetzDepartment of Neurology, University Hospital of Frankfurt, Goethe-University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Christian FoerchDepartment of Neurology, University Hospital of Frankfurt, Goethe-University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fasting Ramadan is known to influence patients' medication adherence. Data on patients' behavior to oral anticoagulant (OAC) drug intake during Ramadan is missing. We aimed to determine patient-guided modifications of OAC medication regimen during Ramadan and to evaluate its consequences. A multicenter cross-sectional study conducted in Saudi Arabia. Data were collected shortly after Ramadan 2019. Participants were patients who fasted Ramadan and who were on long-term anticoagulation. Patient-guided medication changes during Ramadan in comparison to the regular intake schedule before Ramadan were recorded. Modification behavior was compared between twice daily (BID) and once daily (QD) treatment regimens. Rates of hospital admission during Ramadan were determined. We included 808 patients. During Ramadan, 53.1% modified their intake schedule (31.1% adjusted intake time, 13.2% skipped intakes, 2.2% took double dosing). A higher frequency of patient-guided modification was observed in patients on BID regimen compared to QD regimen. During Ramadan, 11.3% of patients were admitted to hospital. Patient-guided modification was a strong predictor for hospital admission. Patient-guided modification of OAC intake during Ramadan is common, particularly in patients on BID regimen. It increases the risk of hospital admission during Ramadan. Planning of OAC intake during Ramadan and patient education on the risk of low adherence are advisable.

Indexed as

FastingAdministration, OralAdultAgedAnticoagulantsCross-Sectional StudiesFemaleHumansMaleMedication AdherenceMiddle AgedReligion and MedicineSaudi ArabiaAnticoagulantsAdherenceEducationFastingOral anticoagulationRamadanSaudi Arabia

Identifiers

PMID32666427
PMCPMC7886720

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.