Evidence map›Paper›PMID 32666401›Full record

ArticleEJNMMI physics2020

Quantitative

M Stella, Ajat Braat, Mgeh Lam, Hwam de Jong, R van Rooij

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02067988 (Adjuvant Hepatic Holmium-166-radioembolization in Patients With Unresectable Liver Metastases of Neuroendocrine Origin, Who Have Been Treated With Lutetium-177-dotatate), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02067988 phase2completednot on this map

Adjuvant Hepatic Holmium-166-radioembolization in Patients With Unresectable Liver Metastases of Neuroendocrine Origin, Who Have Been Treated With Lutetium-177-dotatate

TypeinterventionalSponsorUMC UtrechtRan2014 to 2019Enrolled34ConditionsNeuroendocrine TumorsArmsHolmium-166 microspheres hepatic radioembolization.
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025
    Review
  3. Article
  4. Article
  5. Holmium-166 Radioembolization: Current Status and Future Prospective.Cardiovascular and interventional radiology · 2022
    Review
  6. EJNMMI physics · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

M StellaDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands. Stella@umcutrecht.nl.ORCID https://orcid.org/0000-0001-9794-3184
Ajat BraatDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-8824-8697
Mgeh LamDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-4902-9790
Hwam de JongDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-3000-8316
R van RooijDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-8546-8283
Heidelberg University · DEUtrecht University · NL

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek R4873
6 · The paper itself

Abstract

purposeAccurate dosimetry is essential in radioembolization. To this purpose, an automatic protocol for healthy liver dosimetry based on dual isotope (DI) SPECT imaging, combining holmium-166 (

methodsThe

resultsThe qualitative assessment showed no distinct clinical preference for either

conclusionThe DI protocol enables automatic dosimetry with undiminished image quality and accuracy. CLINICAL TRIALS: The clinical study mentioned is registered with Clinicaltrials.gov (NCT02067988) on 20 February 2014.

Indexed as

Dual isotopeHolmium-166RadioembolizationScatter correctionSPECT/CTTechnetium

Identifiers

PMID32666401
PMCPMC7359973
OpenAlexW3043689876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.