Evidence map›Paper›PMID 32666315›Full record

ArticleJournal of abnormal child psychology2020

Subgroups of Childhood ADHD Based on Temperament Traits and Cognition: Concurrent and Predictive Validity.

Patrick K Goh, Christine A Lee, Michelle M Martel, Sarah L Karalunas, Joel T Nigg

Abstract read
In one paragraph

Article in Journal of abnormal child psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Reproducible Temperament Profiles in Adolescents With Attention-Deficit/Hyperactivity Disorder Prospectively Predict Clinical Outcomes.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  2. Article
  3. Article
  4. Exploring Transdiagnostic Mechanisms of Youth Externalizing Psychopathology: A Longitudinal Person-Centered Approach.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Transdiagnostic Behavioral Phenotypes and Comorbid Gastrointestinal Symptoms in Neurodevelopmental Disorders: An Exploratory Study.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  9. Developmental Pathways of Inattention, Hyperactivity/Impulsivity, and Disruptive Behaviors: A Longitudinal, Person-Centered Approach.Clinical psychological science : a journal of the Association for Psychological Science · 2025
    Article
  10. Article
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  12. Clinical subtyping using community detection: Limited utility?International journal of methods in psychiatric research · 2023
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  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrick K GohDepartment of Psychology, University of Kentucky, Lexington, KY, USA. pat.goh@uky.edu.ORCID 0000-0002-5454-4885
Christine A LeeDepartment of Psychiatry and Behavioral Health, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Michelle M MartelDepartment of Psychology, University of Kentucky, Lexington, KY, USA.
Sarah L KaralunasDepartment of Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Joel T NiggDepartment of Psychiatry, Oregon Health & Science University, Portland, OR, USA.

Funding

ADHD heterogeneity, mechanisms, and risk profileR37MH059105 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI NIGG, JOEL T · 2014 to 2023
$7.0M
Biobehavioral validation of the ADHD emotion dysregulation phenotypeR01MH120109 · NIMH · PURDUE UNIVERSITY · PI KARALUNAS, SARAH LYN · 2020 to 2025
$2.9M
Neurophysiological mechanisms of cognitive and emotional control in ADHDK23MH108656 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI KARALUNAS, SARAH LYN · 2016 to 2019
$742k
NIMH NIH HHS K23 MH108656NIMH NIH HHS R01 MH120109NIMH NIH HHS R37 MH059105
6 · The paper itself

Abstract

Efforts to parse ADHD's heterogeneity in the DSM system has generally relied on subtypes, or presentations, based on different symptom combinations. Promising recent work has suggested that biologically-relevant and clinically predictive subgroups may be identified via an alternative feature set based on either a) temperament traits or b) executive function measures. Yet, the potential additive ability of these domains for specifying ADHD sub-phenotypes remains unknown. We thus sought to determine whether temperament traits and executive function, together, could facilitate a more nuanced and clinically meaningful subgrouping of children with ADHD. Participants included 828 children aged 7-11 years (62% with ADHD, 38% female). Latent profile and community detection analyses using both temperament and cognitive input features provided support for a primarily temperament-based three-subgroup solution (i.e., "Mild," "Irritable," and "Surgent"), although the distinction between Surgent and Mild subgroups may have been better explained as an ADHD symptom severity effect. There was also evidence of a five-subgroup solution, in which cognitive measures differentiated the Surgent subgroup into those with and without cognitive impairment. Cognitive measures also appeared to differentiate the Irritable subgroup based on severity, although differences in resulting subgroups appeared better explained via differences in negative affect and shyness. Subgroups within the five-subgroup solution meaningfully differed with respect to concurrent comorbidity. The utility of the five-subgroup solution for predicting comorbid diagnoses 2 years later was more limited. Additional work is needed to fully characterize the integration of cognitive and affective functioning in ADHD and their overlapping or additive value for clinical prediction.

Indexed as

CognitionTemperamentAttention Deficit Disorder with HyperactivityChildFemaleHumansIrritable MoodMaleReproducibility of ResultsSurveys and QuestionnairesChildhood ADHDCognitionLatent profile analysisSubgroupingTemperament traits

Identifiers

PMID32666315
PMCPMC8647195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.