Evidence map›Paper›PMID 32666099›Full record

ArticleBrain : a journal of neurology2020

Reply: CYLD variants in frontotemporal dementia associated with severe memory impairment in a Portuguese cohort.

Lisa J Oyston, Zac Chatterton, Marianne Hallupp, Neil Rajan, John B Kwok, Carol Dobson-Stone

Open access · bronzeAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain : a journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Role of CYLD in brain physiology and pathology.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  2. CYLD in health and disease.Disease models & mechanisms · 2023
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Lisa J OystonThe University of Sydney, Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, Camperdown, NSW 2006, Australia.
Zac ChattertonThe University of Sydney, Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, Camperdown, NSW 2006, Australia.
Marianne HalluppThe University of Sydney, Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, Camperdown, NSW 2006, Australia.
Neil RajanTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK.
John B KwokThe University of Sydney, Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, Camperdown, NSW 2006, Australia.
Carol Dobson-StoneThe University of Sydney, Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, Camperdown, NSW 2006, Australia.
University of Sydney · AUIcahn School of Medicine at Mount Sinai · USNewcastle University · GBUNSW Sydney · AU

Funding

Alzheimer's Disease Genetics ConsortiumU01AG032984 · NIA · UNIVERSITY OF PENNSYLVANIA · PI SCHELLENBERG, GERARD DAVID · 2009 to 2024
$60.4M
Genome Center for Alzheimer's Disease (GCAD)U54AG052427 · NIA · UNIVERSITY OF PENNSYLVANIA · PI SCHELLENBERG, GERARD DAVID, WANG, LI-SAN · 2016 to 2025
$32.8M
Consortium for Alzheimers Sequence Analysis (CASA)UF1AG047133 · NIA · UNIVERSITY OF PENNSYLVANIA · PI FARRER, LINDSAY A., HAINES, JONATHAN L · 2014 to 2014
$12.6M
Replication and Extension of ADSP Discoveries in African-AmericansU01AG052410 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BEECHAM, GARY WAYNE, BYRD, GOLDIE S. · 2016 to 2020
$5.2M
Identification and characterization of AD risk networks using multi-dimensional "omics" dataU01AG052411 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CRUCHAGA, CARLOS, GOATE, ALISON M · 2016 to 2020
$4.5M
Collaborative GWAS of Dementia, AD and related MRI and Cognitive EndophenotypesR01AG033193 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SESHADRI, SUDHA · 2009 to 2016
$4.4M
Sequence-based Discovery of AD Risk & Protective AllelesU01AG049506 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BOERWINKLE, ERIC A., SALERNO, WILLIAM JAMES · 2014 to 2017
$3.8M
CHARGE: Identifying Risk & Protective SNV for AD in ADSP Case-control SampleU01AG049505 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SESHADRI, SUDHA · 2014 to 2017
$3.0M
Sequence-based Discovery of AD Risk & Protective AllelesU01AG049507 · NIA · UNIVERSITY OF WASHINGTON · PI WIJSMAN, ELLEN M · 2014 to 2017
$2.9M
Modifier Genes that Influence Age at Onset or Protect Against Development of Alzheimer's Disease (AD)U01AG049508 · NIA · WASHINGTON UNIVERSITY · PI GOATE, ALISON M · 2014 to 2017
$1.8M
ADSP Follow-up in Multi-Ethnic Cohorts via Endophenotypes, Omics & Model SystemsU01AG052409 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FORNAGE, MYRIAM, SESHADRI, SUDHA · 2016 to 2020
$1.6M
Department of Health [UK]NIA NIH HHS R01 AG033193NIA NIH HHS U01 AG032984NIA NIH HHS U01 AG049505NIA NIH HHS U01 AG049506NIA NIH HHS U01 AG049507NIA NIH HHS U01 AG049508NIA NIH HHS U01 AG052409NIA NIH HHS U01 AG052410NIA NIH HHS U01 AG052411NIA NIH HHS U54 AG052427NIA NIH HHS UF1 AG047133Wellcome TrustWellcome Trust 100935/Z/13/ZWellcome Trust WT097163MA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyotrophic Lateral SclerosisFrontotemporal DementiaPick Disease of the BrainDeubiquitinating Enzyme CYLDHumansMemory DisordersPortugalCYLD protein, humanDeubiquitinating Enzyme CYLD

Identifiers

PMID32666099
PMCPMC7447510
OpenAlexW3025291583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.