ArticleOpen forum infectious diseases2020
The Impact of Influenza Vaccination on Antibiotic Use in the United States, 2010-2017.
Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 37 citations in OpenAlex.
- The Effectiveness of Nirsevimab on Antibiotic Use in Children Using Target Trial Emulation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Climate change and antimicrobial resistance.Nature reviews. Microbiology · 2026Review
- Influenza Vaccination in Spain: Understanding the Impact of Suboptimal Coverage on Health, Society, and the Economy.Vaccines · 2026Review
- Article
- Factors influencing antibiotic prescription for respiratory tract infections among prescribers in Jinja City, Uganda: a qualitative study.BMC pulmonary medicine · 2026Article
- Pediatric Antibiotic Use Associated With Respiratory Syncytial Virus and Influenza in the United States, 2008-2018.The Journal of infectious diseases · 2025Article
- The Central Importance of Vaccines to Mitigate the Threat of Antibiotic-Resistant Bacterial Pathogens.Vaccines · 2025Review
- Temporal trends in vaccination and antibiotic use among young children in the United States, 2000-2019.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Factors associated with antibiotic use in children hospitalized for acute viral gastroenteritis and the relation to rotavirus vaccination.Human vaccines & immunotherapeutics · 2024Article
- Global trends in antibiotic consumption during 2016-2023 and future projections through 2030.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Routine immunization againstThe Lancet regional health. Southeast Asia · 2024Article
- Prescription patterns of antibiotics and associated factors among outpatients diagnosed with respiratory tract infections in Jinja city, Uganda, June 2022-May 2023.BMC pulmonary medicine · 2024Observational
- Impact of COVID-19 on antibiotic usage in primary care: a retrospective analysis.Scientific reports · 2024Article
- Vaccination to Reduce Antimicrobial Resistance Burden-Data Gaps and Future Research.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Association between seasonal influenza vaccination and antimicrobial use in Japan from the 2015-16 to 2020-21 seasons: from the VENUS study.The Journal of antimicrobial chemotherapy · 2023Article
- Antibiotic persistence and its impact on the environment.3 Biotech · 2023Review
- The burden of influenza and the role of influenza vaccination in adults aged 50-64 years: A summary of available evidence.Human vaccines & immunotherapeutics · 2023Review
- COVID-19 and Outpatient Antibiotic Prescriptions in the United States: A County-Level Analysis.Open forum infectious diseases · 2023Article
- Global antibiotic use during the COVID-19 pandemic: analysis of pharmaceutical sales data from 71 countries, 2020-2022.EClinicalMedicine · 2023Article
- Available evidence and potential for vaccines for reduction in antibiotic prescriptions.Human vaccines & immunotherapeutics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfluenza, which peaks seasonally, is an important driver for antibiotic prescribing. Although influenza vaccination has been shown to reduce severe illness, evidence of the population-level effects of vaccination coverage on rates of antibiotic prescribing in the United States is lacking.
methodsWe conducted a retrospective analysis of influenza vaccination coverage and antibiotic prescribing rates from 2010 to 2017 across states in the United States, controlling for differences in health infrastructure and yearly vaccine effectiveness. Using data from IQVIA's Xponent database and the US Centers for Disease Control and Prevention's FluVaxView, we employed fixed-effects regression analysis to analyze the relationship between influenza vaccine coverage rates and the number of antibiotic prescriptions per 1000 residents from January to March of each year.
resultsWe observed that, controlling for socioeconomic differences, access to health care, childcare centers, climate, vaccine effectiveness, and state-level differences, a 10-percentage point increase in the influenza vaccination rate was associated with a 6.5% decrease in antibiotic use, equivalent to 14.2 (95% CI, 6.0-22.4;
conclusionsIncreased influenza vaccination uptake at the population level is associated with state-level reductions in antibiotic use. Expanding influenza vaccination could be an important intervention to reduce unnecessary antibiotic prescribing.
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Registered trials
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