ArticleJournal of clinical and experimental dentistry2020
Oral leukoplakia, a clinical-histopathological study in 412 patients.
Article in Journal of clinical and experimental dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Knowledge, Attitude, and Practice of Dutch Dentists on Oral Leukoplakia and Their Possible Role in Its Follow-Up.International dental journal · 2025Article
- Malignant Transformed and Non-Transformed Oral Leukoplakias Are Metabolically Different.International journal of molecular sciences · 2025Article
- Artificial intelligence-based diagnosis of oral leukoplakia using deep convolutional neural networks Xception and MobileNet-v2.Frontiers in oral health · 2025Article
- Oral Leukoplakia. A Five-Year Follow-Up Study.Maedica · 2023Article
- Clinical roles of autophagy-related proteins Beclin-1 and mTOR in smoking and non-smoking patients with oral leukoplakia.African health sciences · 2023Article
- Associations between clinical and histopathological characteristics in oral leukoplakia.Oral diseases · 2023Article
- Article
- Gingival Leukoplakia: Hyperkeratosis with Epithelial Atrophy Is A Frequent Histopathologic Finding.Head and neck pathology · 2021Article
- Importance of the PD-1/PD-L1 Axis for Malignant Transformation and Risk Assessment of Oral Leukoplakia.Biomedicines · 2021Article
- The Analysis of the Frequency of Leukoplakia in Reference of Tobacco Smoking among Northern Polish Population.International journal of environmental research and public health · 2020Article
Corrections and comments
- Retraction · 2021-05-01Error in Data · Retract and Replace ·
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA retrospective clinical-histopathological study was made of the evolution of oral leukoplakia over time, staging the disease according to the classification of van der Waal. MATERIAL AND
methodsA study was made of 412 patients with oral leukoplakia, analyzing the corresponding clinical factors and histopathological findings; assessing associations between the different clinical presentations and epithelial dysplasia; and evaluating the factors influencing malignant transformation of the lesions.
resultsClinically, homogeneous presentations were seen to predominate (n = 336, 81.6%), while histologically most of the lesions exhibited no dysplastic changes (n = 271; 65.7%). Stage 1 of the van der Waal classification was the most common presentation (n = 214; 51.9%). The lesion malignization rate was 8.3%, and the factors associated to a significantly increased malignization risk were non-homogeneous OL lesions (
conclusionsIn our series of patients with oral leukoplakia, malignization was associated to the less common clinical presentations of the disease, i.e., non-homogeneous lesions, and the latter tended to exhibit high grade epithelial dysplasia.
Identifiers
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Registered trials
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