Evidence map›Paper›PMID 32665612›Full record

ArticleInternational journal of obesity (2005)2020

Sensitization of the reinforcing value of food: a novel risk factor for overweight in adolescents.

Jennifer L Temple, Amanda M Ziegler, Amanda K Crandall, Tegan Mansouri, Leonard H Epstein

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Observational
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  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer L TempleDepartments of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, NY, 14214, USA. jltemple@buffalo.edu.ORCID http://orcid.org/0000-0002-1670-1501
Amanda M ZieglerDepartments of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, NY, 14214, USA.
Amanda K CrandallCommunity Health and Health Behavior, University at Buffalo, Buffalo, NY, 14214, USA.
Tegan MansouriDepartments of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, NY, 14214, USA.
Leonard H EpsteinDepartment of Pediatrics, University at Buffalo, Buffalo, NY, 14214, USA.ORCID http://orcid.org/0000-0003-1167-8848

Funding

New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Sensitization of the reinforcing value of food as a predictor of weight change in adolescentsR01DK106265 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI TEMPLE, JENNIFER L · 2016 to 2020
$1.9M
NIDDK NIH HHS P30 DK111022NIDDK NIH HHS R01 DK106265
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe relative reinforcing value (RRV) of food is associated with increased energy intake and obesity and increases in RRV of food after repeated intake (sensitization) are related cross-sectionally and prospectively to higher BMI in adults. We examined the factors, such as delay discounting (DD), associated with sensitization of RRV to high energy density (HED) and low energy density (LED) food and how sensitization relates to zBMI in adolescents. We hypothesized that sensitization to HED food would be positively associated with zBMI, that sensitization to LED food would be negatively associated with zBMI, that DD would be associated with HED sensitization, and that LED sensitization and DD would moderate the relationships between HED sensitization and zBMI. SUBJECTS AND

methodsA population-based sample of 207 adolescents without obesity, aged 12-14 years was studied from June 2016-March 2019. The RRV of LED and HED foods were measured before and after two weeks of daily consumption along with zBMI and other potential factors related to eating and weight, including dietary restraint, hunger, food liking, and delay discounting (DD). Hierarchical regression models were used to determine the associations between these factors and sensitization and zBMI. We also examined LED sensitization and DD as potential moderators of the relationship between sensitization and zBMI.

resultsAs hypothesized, dietary restraint and sensitization to HED food were associated with greater zBMI. Contrary to our original hypotheses, DD was not associated with sensitization, there was no relationship between sensitization to LED food and zBMI and neither LED sensitization or DD moderated the relationship between HED sensitization and zBMI.

conclusionsSensitization to repeated intake of HED food was associated with higher zBMI in adolescents without obesity. Sensitization may be a novel behavioral phenotype that may relate to overweight in youth.

Indexed as

Reinforcement, PsychologyAdolescentChildDiet SurveysFeeding BehaviorFemaleHumansLongitudinal StudiesMalePediatric ObesityRisk Factors

Identifiers

PMID32665612
PMCPMC7484379

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.