ArticleScience signaling2020
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca
Open access · greenAbstract read
In one paragraph
Article in Science signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 66 citations in OpenAlex.
- InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity.Nature communications · 2026Article
- Autophagy-Apoptosis Crosstalk in Cancer: Mechanisms, Signaling Pathways, and Therapeutic Targeting.Cancers · 2026Review
- Organelle contact sites in cancer cells.Cell death & disease · 2026Review
- InsP3R signaling mediates mitochondrial stress-induced longevity through actomyosin-dependent mitochondrial dynamics.bioRxiv : the preprint server for biology · 2025Article
- Deciphering the Regulatory Potential of Antioxidant and Electron-Shuttling Bioactive Compounds in Oolong Tea.Biology · 2025Article
- Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis.Molecular cell · 2025Review
- CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer.Nature communications · 2025Article
- Implications for the role of natural products in Parkinson disease therapy.Archives of medical science : AMS · 2025Article
- Deciphering Mitochondria: Unveiling Their Roles in Mechanosensing and Mechanotransduction.Research (Washington, D.C.) · 2025Review
- Harnessing Nature's Bounty: The Neuroprotective Potential of Phytoconstituents and Nanotechnology in Neurodegenerative Disease Therapeutics.CNS & neurological disorders drug targets · 2025Review
- The IPBiochimica et biophysica acta. Molecular basis of disease · 2025Article
- Nanotechnology-Fortified Manipulation of Cell CaSmall science · 2024Article
- Mitochondrial division inhibitor (mdivi-1) induces extracellular matrix (ECM)-detachment of viable breast cancer cells by a DRP1-independent mechanism.Scientific reports · 2024Article
- Aberrant ER-mitochondria communication is a common pathomechanism in mitochondrial disease.Cell death & disease · 2024Article
- Scalable Total Synthesis of (+)-Desmethylxestospongin B.The Journal of organic chemistry · 2024Article
- Article
- Cell-surface photochemistry mediated calcium overload for synergistic tumor therapy.Journal of nanobiotechnology · 2023Article
- The mitochondrial CabioRxiv : the preprint server for biology · 2023Article
- Sustained IP3-linked CaFrontiers in cell and developmental biology · 2023Article
- The mitochondrial CaFrontiers in cell and developmental biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 7 institutions in 3 countries.
Cesar CardenasCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile. julio.cardenas@umayor.cl foskett@pennmedicine.upenn.edu.ORCID 0000-0003-1115-2790
Alenka LovyCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.ORCID 0000-0002-8167-3199
Eduardo Silva-PavezCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.
Felix UrraGeroscience Center for Brain Health and Metabolism, Santiago 8580745, Chile.ORCID 0000-0001-8582-4399
Craig MizzoniDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Ulises Ahumada-CastroCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.
Galdo BustosCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.ORCID 0000-0002-4430-4271
Fabian JaňaGeroscience Center for Brain Health and Metabolism, Santiago 8580745, Chile.ORCID 0000-0001-7786-4569
Pablo CruzCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.
Paula FariasCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.ORCID 0000-0003-2250-953X
Elizabeth MendozaCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.ORCID 0000-0002-5802-8693
Hernan HuertaCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.ORCID 0000-0002-7392-3311
Paola MurgasCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.
Martin HunterDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.ORCID 0000-0001-7928-8518
Melany RiosCenter for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago 8580745, Chile.
Oscar CerdaProgram of Cellular and Molecular Biology, Institute of Biomedical Sciences (ICBM), Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID 0000-0003-2873-5722
Irene GeorgakoudiDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.ORCID 0000-0002-0049-6697
Armen ZakarianDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Jordi MolgóUniversité Paris-Saclay, CEA, Institut des Sciences du Vivant Frédéric Joliot, ERL CNRS n° 9004, Département Médicaments et Technologies pour la Santé, Service d'Ingénierie Moléculaire pour la Santé (SIMoS), bâtiment 152, Point courrier 24, F-91191 Gif sur Yvette, France.ORCID 0000-0002-0693-8994
J Kevin FoskettDepartments of Physiology and Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. julio.cardenas@umayor.cl foskett@pennmedicine.upenn.edu.ORCID 0000-0002-8854-0268
Universidad Mayor · CLTufts University · USCenter for Climate and Resilience Research · CLCentre National de la Recherche Scientifique · FRMinistry of Health · CLUniversity of California, Santa Barbara · USUniversity of Pennsylvania · US
Funding
TUSM/T-NEMC CENTER FOR NEUROSCIENCE RESEARCH - Imaging CoreP30NS047243 · NINDS · TUFTS UNIVERSITY BOSTON · PI JACKSON, F ROB · 2003 to 2017
$10.0MElectrophysiology of nuclear membrane InsP3 receptorR37GM056328 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2011 to 2020
$4.9MAcquisition of Leica confocal/multiphoton microscopeS10OD021624 · OD · TUFTS UNIVERSITY MEDFORD · PI GEORGAKOUDI, IRENE · 2016 to 2016
$600kNIGMS NIH HHS R37 GM056328NIH HHS S10 OD021624NINDS NIH HHS P30 NS047243
Abstract
Spontaneous Ca
Indexed as
Oxidative PhosphorylationCalciumCell Line, TumorCell SurvivalEndoplasmic ReticulumHumansMitochondriaMitochondrial ProteinsNeoplasm ProteinsNeoplasmsCalciumMitochondrial ProteinsNeoplasm Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.