Evidence map›Paper›PMID 32665410›Full record

Trial reportNeurology2020

Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial.

Nabeel Saif, Kellyann Niotis, Moises Dominguez, John F Hodes, Michael Woodbury, Yasmin Amini, George Sadek, Olivia Scheyer, Emily Caesar, Hollie Hristov and 4 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Alzheimer Caregiving Problems According to ADLs: Evidence from Facebook Support Groups.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Nabeel SaifFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.ORCID 0000-0002-8355-4759
Kellyann NiotisFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Moises DominguezFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
John F HodesFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Michael WoodburyFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Yasmin AminiFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
George SadekFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Olivia ScheyerFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Emily CaesarFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Hollie HristovFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Newman KnowltonFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Paige LeeFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Mark McInnisFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT.
Richard S IsaacsonFrom the Department of Neurology (N.S., K.N., M.D., G.S., H.H., M.M., R.S.I.), Weill Cornell Medicine & New York-Presbyterian, New York; Pacific Brain Health Center (J.F.H.), Pacific Neuroscience Institute, Los Angeles, CA; Harvard Medical School (M.W.), Boston, MA; Mailman School of Public Health (Y.A.), Columbia University, New York, NY; School of Law (O.S.) and College of Letters and Science (P.L.), University of California Los Angeles; Loyola School of Medicine (E.C.), Chicago, IL; and Biostatistics (N.K.), Pentara Corporation, Salt Lake City, UT. rii9004@med.cornell.edu.
NewYork–Presbyterian Hospital · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

objectiveAlzheimer disease (AD) risk factors are present throughout the lifespan. This randomized controlled trial evaluated the effectiveness of various online education strategies concerning AD risk reduction and brain health in younger populations.

methodHigh school and college students were recruited via social media (Facebook and Instagram) to join AlzU.org, an evidence-based education portal, and were randomized to 1 of 4 courses: highly interactive webinar lessons narrated by actor Seth Rogen (celebrity webinar) or a physician (doctor webinar), minimally interactive video lessons with Seth Rogen (celebrity video), or minimally interactive video lessons (control). Surveys were administered at baseline and postcourse. The primary outcome was change in knowledge of AD risk reduction assessed by pre vs post lesson quiz scores. Secondary outcomes included change in awareness of AD research, hopefulness about AD, interest in pursuing health care, willingness to volunteer, and likelihood of recommending AlzU.org.

resultA total of 721 participants joined. A total of 281 (38.9%) completed the course. Among college students, quiz score improvements were greater in celebrity webinar and celebrity video vs doctor webinar and control. Among high school students, no differences were found in quiz scores. In both groups, celebrity webinar, celebrity video, and doctor webinar resulted in greater improvements in awareness that nutrition and exercise may reduce AD risk vs controls. Among college students, celebrity webinar and celebrity video group participants felt more hopeful about the future of AD and more likely to recommend AlzU.org vs doctor webinar and control participants. Among college students, celebrity webinar, celebrity video, and doctor webinar participants were more willing to volunteer for AD causes and pursue health care careers vs controls.

conclusionOnline education involving a celebrity may be an effective strategy for educating college students about AD risk reduction strategies. Further studies are warranted in high school students.

Indexed as

AdolescentAdultAlzheimer DiseaseEducation, DistanceFamous PersonsFemaleHealth EducationHealth Knowledge, Attitudes, PracticeHealth PromotionHumansInternetMaleRisk Reduction BehaviorStudentsYoung Adult

Identifiers

PMID32665410
PMCPMC7713789
OpenAlexW3043652378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.