ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
Circuit Mechanisms Underlying the Segregation and Integration of Parallel Processing Streams in the Inferior Colliculus.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Ascending inputs to inferior colliculus subdivisions reveal pathway-specific hybrid organization in the external cortex.bioRxiv : the preprint server for biology · 2026Article
- A Protocol for Microprism-Based Two-Photon Imaging Of The Lateral Cortex In The Mouse Inferior Colliculus.Current protocols · 2026Article
- Age-related ultrastructural differences in the dorsal cortex of the inferior colliculus in the fischer brown Norway rat.Neurobiology of aging · 2026Article
- A midbrain circuit mechanism for noise-induced negative valence coding.Nature communications · 2025Article
- Article
- Microglial Engulfment of Multisensory Terminals in the Midbrain Inferior Colliculus During an Early Critical Period.The Journal of comparative neurology · 2025Article
- Role of the Dorsal Cortex of the Inferior Colliculus in the Precedence Effect.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Population coding of time-varying sounds in the nonlemniscal inferior colliculus.Journal of neurophysiology · 2024Article
- Headplate Installation and Craniotomy for Awake In Vivo Electrophysiological Recordings or Two-Photon Imaging of the Mouse Inferior Colliculus.Bio-protocol · 2023Article
- Gradients of response latencies and temporal precision of auditory neurons extend across the whole inferior colliculus.Journal of neurophysiology · 2023Article
- Population coding of time-varying sounds in the non-lemniscal Inferior Colliculus.bioRxiv : the preprint server for biology · 2023Article
- Eph and ephrin signaling in the development of the central auditory system.Developmental dynamics : an official publication of the American Association of Anatomists · 2023Review
- Age-related ultrastructural changes in the lateral cortex of the inferior colliculus.Neurobiology of aging · 2022Article
- Diverse functions of the auditory cortico-collicular pathway.Hearing research · 2022Review
- Article
- Corticofugal regulation of predictive coding.eLife · 2022Article
- Segregation of Multimodal Inputs Into Discrete Midbrain Compartments During an Early Critical Period.Frontiers in neural circuits · 2022Article
- Microglial heterogeneity and complement component 3 elimination within emerging multisensory midbrain compartments during an early critical period.Frontiers in neuroscience · 2022Article
- Inferior collicular cells that project to the auditory thalamus are increasingly surrounded by perineuronal nets with age.Neurobiology of aging · 2021Article
- Registry of Compartmental Ephrin-B3 Guidance Patterns With Respect to Emerging Multimodal Midbrain Maps.Frontiers in neuroanatomy · 2021Article
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3 authors.
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Abstract
The lateral cortex of the inferior colliculus (LCIC) forms a nexus between diverse multisensory, motor, and neuromodulatory streams. Like other integration hubs, it contains repeated neurochemical motifs with distinct inputs: GABA-rich modules are innervated by somatosensory structures, while auditory inputs to the LCIC target the surrounding extramodular matrix. To investigate potential mechanisms of convergence between these input streams, we used laser photostimulation circuit mapping to interrogate local LCIC circuits in adult mice of both sexes and found that input patterns are highly dependent on cell type (GABAergic/non-GABAergic) and location (module/matrix). At the circuit level, these inputs yield a directional flow of local information, primarily from the matrix to the modules. Further, the two compartments were found to project to distinct targets in the midbrain and thalamus. These data show that, while connectional modularity in the LCIC gives rise to segregated input-output channels, local circuits provide the architecture for integration between these two streams.
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