Evidence map›Paper›PMID 32665399›Full record

ArticleThe Journal of biological chemistry2020

Glycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation machinery.

Vignesh Venkatakrishnan, Régis Dieckmann, Ian Loke, Harry C Tjondro, Sayantani Chatterjee, Johan Bylund, Morten Thaysen-Andersen, Niclas G Karlsson, Anna Karlsson-Bengtsson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Expedient Assembly of MultiantennaryJournal of the American Chemical Society · 2025
    Article
  5. Article
  6. Article
  7. Glycoproteome remodeling and organelle-specificProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The mannose receptor ligands and the macrophage glycome.Current opinion in structural biology · 2022
    Review
  13. Article
  14. Review
  15. Article
  16. SerumJournal of clinical medicine · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Vignesh VenkatakrishnanDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden vignesh.venkatakrishnan@gu.se.ORCID 0000-0001-5671-1547
Régis DieckmannDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ian LokeDepartment of Molecular Sciences, Macquarie University, Sydney, Australia.ORCID 0000-0002-2558-0975
Harry C TjondroDepartment of Molecular Sciences, Macquarie University, Sydney, Australia.ORCID 0000-0001-5037-0091
Sayantani ChatterjeeDepartment of Molecular Sciences, Macquarie University, Sydney, Australia.ORCID 0000-0002-7007-0333
Johan BylundDepartment of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Morten Thaysen-AndersenDepartment of Molecular Sciences, Macquarie University, Sydney, Australia.ORCID 0000-0001-8327-6843
Niclas G KarlssonDepartment of Medical Chemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-3045-2628
Anna Karlsson-BengtssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6796-1154
University of Gothenburg · SEMacquarie University · AUChalmers University of Technology · SECordlife (Singapore) · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein glycosylation is essential to trafficking and immune functions of human neutrophils. During granulopoiesis in the bone marrow, distinct neutrophil granules are successively formed. Distinct receptors and effector proteins, many of which are glycosylated, are targeted to each type of granule according to their time of expression, a process called "targeting by timing." Therefore, these granules are time capsules reflecting different times of maturation that can be used to understand the glycosylation process during granulopoiesis. Herein, neutrophil subcellular granules were fractionated by Percoll density gradient centrifugation, and

Indexed as

Cytoplasmic GranulesGlycosylationHumansLewis X AntigenNeutrophilsPolysaccharidesSialyl Lewis X AntigenLewis X AntigenLewis x oligosaccharidePolysaccharidesSialyl Lewis X AntigenglycosylationgranuleLacNAcLewis epitopeliquid chromatographymass spectrometry (MS)neutrophilN-glycanN-linked glycosylationO-glycanplasma membranetargeting by timing

Identifiers

PMID32665399
PMCPMC7476722
OpenAlexW3043669394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.