Evidence map›Paper›PMID 32665393›Full record

ArticleBMJ open2020

Improving the HIV PrEP continuum of care using an intervention for healthcare providers: a stepped-wedge study protocol.

Kristin Ming, Isha Shrestha, Alexander Vazquez, James Wendelborn, Veronica Jimenez, Nadra Lisha, Torsten B Neilands, Hyman Scott, Albert Liu, Wayne Steward and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03532191 (Improving the HIV PrEP Cascade Using an Intervention for Healthcare Providers), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03532191 nacompletednot on this map

Improving the HIV PrEP Cascade Using an Intervention for Healthcare Providers

TypeinterventionalSponsorUniversity of California, San FranciscoRan2018 to 2021Enrolled10ConditionsHIV/AIDSArmsPrEP Optimization Intervention (PrEP-OI)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Implementing PrEP Services in Diverse Health Care Settings.Journal of acquired immune deficiency syndromes (1999) · 2022
    Article
  9. Article
  10. Article
  11. Knowledge, Attitudes, and Intentions towards HIV Pre-Exposure Prophylaxis among Nursing Students in Spain.International journal of environmental research and public health · 2020
    Observational
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kristin Ming *Department of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-0688-9002
Isha Shrestha *Department of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Alexander VazquezDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
James WendelbornDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Veronica JimenezDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Nadra LishaDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Torsten B NeilandsDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Hyman ScottBridge HIV, San Francisco Department of Public Health, San Francisco, California, USA.
Albert LiuBridge HIV, San Francisco Department of Public Health, San Francisco, California, USA.
Wayne StewardDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Mallory O JohnsonDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA.
Parya SaberiDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, California, USA Parya.Saberi@ucsf.edu.ORCID 0000-0002-3793-5112
University of California, San Francisco · USSan Francisco Department of Public Health · US

Funding

Improving the HIV PrEP Cascade using an Intervention for Healthcare ProvidersR01NR017573 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SABERI, PARYA · 2017 to 2021
$3.4M
NINR NIH HHS R01 NR017573
6 · The paper itself

Abstract

introductionPre-exposure prophylaxis (PrEP) has demonstrated to be a highly effective method for preventing HIV; however, many individuals with PrEP indications are not receiving PrEP. Primary care settings provide an opportunity to offer PrEP to a wide range of patients. In this paper, we describe the PrEP Optimisation Intervention (PrEP-OI), which includes a PrEP Coordinator and a web-based panel management tool (called PrEP-Rx), and is targeted at healthcare providers (HCPs) to increase PrEP uptake and persistence among those at risk for acquiring HIV. METHODS AND ANALYSIS: The PrEP-OI study evaluates the efficacy of the PrEP intervention (PrEP Coordinator + PrEP-Rx) to increase PrEP prescriptions through a stepped-wedge design among 10 primary care clinical sites in the San Francisco Department of Public Health. The number of PrEP initiation prescriptions constitute the primary outcome, and we hypothesise that the mean number of PrEP prescriptions written will significantly increase after the clinics initiate PrEP-OI versus before this intervention. Secondary objectives include: 1-differences in PrEP initiation, duration of use and reasons for discontinuation based on patient's age, race/ethnicity and sex/gender, and by clinic and HCP characteristics, 2-sustainability of the intervention during a 12-month follow-up after the stepped-wedge phase, and 3-facilitators and barriers of PrEP delivery and experiences with the proposed PrEP intervention through qualitative interviews with HCPs. The results of this study can provide valuable insight into methods to reduce the burden of PrEP care on HCPs and improve PrEP continuum of care. ETHICS AND DISSEMINATION: This study and its protocols have been approved by the University of California, San Francisco (UCSF) Institutional Review Board. Study staff will disseminate findings locally (eg, the UCSF Centre for AIDS Prevention Studies' Community Engagement Core), statewide (eg, the California Department of Public Health's Office of AIDS) and nationally and internationally at conferences related to HIV. TRIAL REGISTRATION NUMBER: NCT03532191.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisContinuity of Patient CareHealth PersonnelHumansSan FranciscoAnti-HIV Agentsgeneral medicine (see internal medicine)HIV & AIDSquality in health care

Identifiers

PMID32665393
PMCPMC7454188
OpenAlexW3042887199

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.