SynthesisStroke and vascular neurology2020
Worldwide 1-month case fatality of ischaemic stroke and the temporal trend.
Synthesis in Stroke and vascular neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sex Differences in Case Fatality of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review.Neuroepidemiology · 2024Pooled it
- Pooled incidence and case-fatality of acute stroke in Mainland China, Hong Kong, and Macao: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Different Long-Term Outcomes According to Thrombus Histology in Patients With Acute Ischemic Stroke.Journal of stroke · 2026Article
- Temporal changes in functional outcome and case-fatality after ischaemic stroke and intracerebral haemorrhage in Sweden 2010-2019: an observational study from the Swedish Stroke Register (Riksstroke).European stroke journal · 2026Observational
- National trends in stroke hospitalisations, mortality, and recurrent stroke in Australia and New Zealand.Scientific reports · 2025Article
- Prognostic Value of Plasma Lysophosphatidic Acid and CD62P in the Outcome of Ischemic Stroke.Annals of Indian Academy of Neurology · 2025Article
- Evolution of Hospitalisation Due to Stroke in Italy Before and After the Outbreak of the COVID-19 Epidemic: A Population-Based Study Using Administrative Data.Journal of clinical medicine · 2025Article
- Incidence of First-Ever Stroke, Stroke Events, and Early Case Fatality Rate in China: Results from a National Population-Based Survey.Neuroepidemiology · 2025Article
- Ischemic Stroke in Adults With Congenital Heart Disease: Cumulative Incidence and Associated Factors.Journal of the American Heart Association · 2024Article
- Article
- Perioperative stroke.Nature reviews. Disease primers · 2024Review
- Trends of Sex Differences and Associated Factors in Stroke Outcomes Among Patients With Acute Ischemic Stroke: 2007 to 2018Neurology · 2024Article
- Prognostic model of in-hospital ischemic stroke mortality based on an electronic health record cohort in Indonesia.PloS one · 2024Observational
- 30-day in-hospital stroke case fatality and significant risk factors in sub-Saharan-Africa: A systematic review and meta-analysis.PLOS global public health · 2024Article
- Stroke in Sierra Leone: Case fatality rate and functional outcome after stroke in Freetown.International journal of stroke : official journal of the International Stroke Society · 2023Article
- Patient-level and system-level determinants of stroke fatality across 16 large hospitals in Ghana and Nigeria: a prospective cohort study.The Lancet. Global health · 2023Article
- Elevated white blood cell counts in ischemic stroke patients are associated with increased mortality and new vascular events.Frontiers in neurology · 2023Article
- Article
- Long-Term Trends in Stroke Management and Burden Among Low-Income Women in a Rural Area From China (1992-2019): A Prospective Population-Based Study.Frontiers in neurology · 2021Article
- Stroke in Young Adults: An Indian Perspective.Annals of Indian Academy of NeurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe 1-month case fatality of ischaemic stroke is an essential epidemiological metric. Whereas the case fatality after ischaemic stroke and the temporal trend is uncertain. We aimed to estimate the 1-month case fatality of ischaemic stroke and its temporal trend, as well as its regional variation.
methodsWe searched PubMed and Embase to identify the studies for 1-month case fatality of ischaemic stroke . The population-based studies were included. Two investigators extracted the data and assessed the quality independently. One-month case fatality of ischaemic stroke was estimated using a random effects model. The temporal trend was evaluated using a mixed-effect meta-regression model.
resultsA total of 59 articles with 77 time periods were included. The worldwide 1-month case fatality of ischaemic stroke was 13.5% (95% CI 12.3% to 14.7%). The case fatality was 10.8% (95% CI 8.3% to 13.5%) in Asia, 14.2% (95% CI 12.6% to 15.9%) in Europe, 14.0% (95% CI 11.2% to 17.1%) in South America and Caribbean, 14.0% (95% CI 9.5% to 19.1%) in North America and 12.5% (95% CI 11.1% to 13.9%) in Australia and New Zealand. Overall, there was a non-significant decrease of 0.1% per year in case fatality. It decreased significantly in Europe (-0.2% annually, 95% CI -0.4% to -0.01%) and North America (-0.2% annually, 95% CI -0.4% to -0.04%), increased significantly in Australia and New Zealand (0.2% annually, 95% CI 0.1% to 0.4%), while no evidence of change in other regions.
conclusionThe 1-month case fatality of ischaemic stroke and its temporal trend were divergent across regions. Further studies are needed to address the reason of the regional difference, which will be helpful to guide the effort of reducing stroke burden.
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