ArticleHeart (British Cardiac Society)2020
Sex differences in the association between childhood maltreatment and cardiovascular disease in the UK Biobank.
Article in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Adverse childhood experiences contribute to blood pressure changes in adulthood: a meta-analysis of over 750 000 adults.Journal of global health · 2025Pooled it
- Pooled it
- Observational
- Investigating relationships between loneliness, social isolation and health.Nature communications · 2026Article
- Association of childhood maltreatment with DXA‑derived body composition in middle‑aged and older adults: mediating roles of unhealthy lifestyle and depression.BMC psychiatry · 2026Article
- Rats exposed to a low resource environment in early life display sex differences in blood pressure, autonomic activity, and brain and kidney pro-inflammatory markers during adulthood.Biology of sex differences · 2026Article
- Identification of Mental Health Disorder Symptoms, Predisposing Factors and their Impact on Quality of Life in Young Hypertensive Patients: A Multicenter Longitudinal Study.Clinical practice and epidemiology in mental health : CP & EMH · 2026Article
- Childhood Maltreatment and Cardiovascular Health: Role of Sex and Life's Essential 8 in the U.K. Biobank.JACC. Advances · 2026Article
- Childhood adversity and disordered eating: the mediator role of food reward drive.Frontiers in psychology · 2026Article
- Adverse experiences in childhood and young adulthood, genetic susceptibility, and neurodegenerative disease incidence: a lifespan analysis.European journal of psychotraumatology · 2025Article
- Childhood maltreatment and adult diseases in the general population: the mediating role of smoking and overweight in a time-sequence design.BMC public health · 2025Article
- Lifetime Exposure to Violence and Early Cardiometabolic Risk Factors in a Healthy Swedish Cohort.Journal of the American Heart Association · 2025Article
- Sexual identity, child maltreatment, mental health, and substance use among emerging adults aged 18 to 23 years.Canadian journal of public health = Revue canadienne de sante publique · 2025Article
- Article
- Adverse Childhood Experiences and Accelerated Epigenetic Aging in the Hispanic Community Health Study/Study of Latinos: Nativity as an Effect Modifier.Psychoneuroendocrinology · 2025Article
- Early life adversity and the comorbidity of psychopathology and cardiometabolic disorders: insights from the UK Biobank.BMJ public health · 2025Article
- Article
- Role of Sex, Anxiety, and Resilience in the Association Between Adverse Childhood Experiences and Irritable Bowel Syndrome.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Article
- Uncovering psychologically mediated pathways to cardiovascular diseases: depressive symptoms as a mediator between childhood maltreatment and single or multiple cardiovascular disease comorbidities.Frontiers in psychiatry · 2025Article
- Childhood Exposure to Interparental Physical Violence and Adult Cardiovascular Disease.JAMA network open · 2024Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
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Abstract
objectivesTo assess and compare associations between childhood maltreatment and cardiovascular disease (CVD) in men and women in the UK. In secondary analyses, we also explored possible age differences and associations with early onset CVD (<50 years).
methodsWe included 157 311 participants from the UK Biobank who had information on physical, sexual or emotional abuse, emotional or physical neglect. CVD outcomes were defined as any CVD, hypertensive disease, ischaemic heart disease (IHD) and cerebrovascular disease. These were extracted from self-report, blood pressure measurements, hospital register and death register. The associations between maltreatment and CVD were assessed using Poisson regression with robust variance to estimate risk ratios, stratified by sex and adjusted for socioeconomic and demographic factors.
resultsAll types of maltreatment were associated with increased risk of CVD and IHD in both sexes. Additionally, in women all types of maltreatment were associated with higher risk of hypertensive disease, and all, except emotional neglect, were associated with cerebrovascular disease. In men, all but sexual abuse, were associated with higher risk of hypertensive disease, and all, except physical and sexual abuse, were associated with cerebrovascular disease. Associations were generally stronger in women, and individuals who were younger at baseline had stronger associations of childhood maltreatment with any CVD and IHD, but age differences were less evident when only early onset CVD was considered.
conclusionsChildhood maltreatment was consistently associated with CVD and stronger associations were generally observed in women and seemed to be stronger for early onset CVD.
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