Evidence map›Paper›PMID 32665300›Full record

ArticleImmunoHorizons2020

Bone Marrow-Derived Dendritic Cell Cultures from RAG

Kaveh Abdi, L Michael Thomas, Karen Laky, Mehrnoosh Abshari, Polly Matzinger, Eric O Long

Abstract read
In one paragraph

Article in ImmunoHorizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Guidelines for mouse and human DC generation.European journal of immunology · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaveh AbdiLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852; kabdi@niaid.nih.gov.ORCID 0000-0002-9763-3757
L Michael ThomasLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.
Karen LakyLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.ORCID 0000-0002-8197-3941
Mehrnoosh AbshariNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-4217-0625
Polly MatzingerLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.
Eric O LongLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.ORCID 0000-0002-7793-3728

Funding

NIDCR DIR Scientific Cores (Combined Technical Research Core)ZICDE000729 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI ABSHARI, MEHRNOOSH · 2009 to 2025
$31.7M
Regulation of innate lymphocyte functionZIAAI000525 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LONG, ERIC O · 2009 to 2024
$12.0M
Intramural NIH HHS Z99 AI999999
6 · The paper itself

Abstract

Dendritic cells (DCs) play a key role in the initiation of an immune response and are known as "professional" APCs because of their ability to activate naive T cells. A widely used method to generate DCs in vitro is to culture bone marrow (BM) cells or blood monocytes in the presence of GM-CSF and IL-4. In this study, we show that a small population of NK cells residing in the BM of RAG

Indexed as

AnimalsBone Marrow CellsCell DifferentiationDendritic CellsFemaleGranulocyte-Macrophage Colony-Stimulating FactorHomeodomain ProteinsInterferon-gammaInterleukin-4Killer Cells, NaturalLipopolysaccharidesLymphocyte ActivationMaleMiceMice, Inbred C57BLMice, KnockoutGranulocyte-Macrophage Colony-Stimulating FactorHomeodomain ProteinsInterferon-gammaInterleukin-4LipopolysaccharidesRAG-1 protein

Identifiers

PMID32665300
PMCPMC7454002

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.