Evidence map›Paper›PMID 32665277›Full record

ArticleGenetics2020

New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in

Matthew D Vandermeulen, Paul J Cullen

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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  11. Deletion of theMicrobiology spectrum · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew D VandermeulenDepartment of Biological Sciences, University at Buffalo, New York 14260-1300.
Paul J CullenDepartment of Biological Sciences, University at Buffalo, New York 14260-1300 pjcullen@buffalo.edu.ORCID 0000-0002-6703-1480
University at Buffalo, State University of New York · US

Funding

Control of MAPK Signaling by Cell Polarity ProteinsR01GM098629 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CULLEN, PAUL JAMES · 2011 to 2024
$4.4M
NIGMS NIH HHS R01 GM098629
6 · The paper itself

Abstract

MAPK pathways are drivers of morphogenesis and stress responses in eukaryotes. A major function of MAPK pathways is the transcriptional induction of target genes, which produce proteins that collectively generate a cellular response. One approach to comprehensively understand how MAPK pathways regulate cellular responses is to characterize the individual functions of their transcriptional targets. Here, by examining uncharacterized targets of the MAPK pathway that positively regulates filamentous growth in

Indexed as

MAP Kinase Signaling SystemCarrier ProteinsCell DivisionGlycoproteinsGTPase-Activating ProteinsMembrane GlycoproteinsRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCarrier ProteinsFLO11 protein, S cerevisiaeGlycoproteinsGTPase-Activating ProteinsMembrane GlycoproteinsRepressor ProteinsRgd2 protein, S cerevisiaeRPI1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTIP1 protein, S cerevisiaeadhesionexpression profilingfilamentous growthfungal pathogenstranscription

Identifiers

PMID32665277
PMCPMC7463291
OpenAlexW3042960921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.