Evidence map›Paper›PMID 32665090›Full record

ReviewTherapie

Challenges of autoimmune rheumatic disease treatment during the COVID-19 pandemic: A review.

Lucile Grange, Philippe Guilpain, Marie-Elise Truchetet, Jean-Luc Cracowski, French Society of Pharmacology and Therapeutics

Abstract readReview
In one paragraph

Review in Therapie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucile GrangeUniversity Saint-Étienne, 42000 Saint-Étienne, France.
Philippe GuilpainMontpellier's school of medicine, university Montpellier, 34967 Montpellier, France; Department of internal medicine - multi-organ diseases, local referral center for autoimmune diseases, Saint-Éloi university hospital, 34295 Montpellier, France; IRMB, Inserm U1183, CHU Montpellier, Saint-Éloi university hospital, university Montpellier, 34090 Montpellier, France.
Marie-Elise TruchetetUniv. Bordeaux, CHU Bordeaux, 33000 Bordeaux, France.
Jean-Luc CracowskiUniv. Grenoble Alpes, INSERM, HP2, 38000 Grenoble, France. Electronic address: Jean-Luc.Cracowski@univ-grenoble-alpes.fr.
French Society of Pharmacology and Therapeutics

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since December 2019, the COVID-19 pandemic has become a major public health problem. To date, there is no evidence of a higher incidence of COVID in patients with autoimmune rheumatic diseases and we support the approach of maintaining chronic rheumatological treatments. However, once infected there is a small but significant increased risk of mortality. Among the different treatments, NSAIDs are associated with higher rates of complications, but data for other drugs are conflicting or incomplete. The use of certain drugs for autoimmune inflammatory rheumatisms appears to be a potentially interesting options for the treatment. The rationale for their use is based on the immune system runaway and the secretion of pro-inflammatory cytokines (Il1, IL6, TNFα) in severe forms of the disease. Notably, patients on chloroquine or hydroxychloroquine as a treatment for their autoimmune rheumatic disease are not protected from COVID-19.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsAutoimmune DiseasesChloroquineCoronavirus InfectionsCOVID-19HumansHydroxychloroquineIncidencePandemicsPneumonia, ViralRheumatic DiseasesAnti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsChloroquineHydroxychloroquineDexamethasoneHydroxychloroquinePharmacologyRheumatoid arthritisRheumatology

Identifiers

PMID32665090
PMCPMC7320663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.