ArticleBMC medical imaging2020
Roles of contrast-enhanced ultrasonography in identifying volume change of benign thyroid nodule and optical time of secondary radiofrequency ablation.
Article in BMC medical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis comparing tumor progression and complications between radiofrequency ablation and thyroidectomy for papillary thyroid carcinoma.Frontiers in oncology · 2022Pooled it
- Effectiveness of microvascular flow imaging for radiofrequency ablation in recurrent thyroid cancer: comparison with power Doppler imaging.European radiology · 2025Article
- Efficacy of radiofrequency ablation for treatment of toxic thyroid nodules-a narrative review.Gland surgery · 2024Review
- Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up.BMC medical imaging · 2022Article
- Performance of Contrast-Enhanced Ultrasound in Thyroid Nodules: Review of Current State and Future Perspectives.Cancers · 2021Review
- RFA and benign thyroid nodules: Review of the current literature.Laryngoscope investigative otolaryngology · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUltrasonography-guided radiofrequency ablation (RFA) was was proved to be an effective and safe treatment with few complications for benign thyroid nodule. In cases of incompletely treated nodule margin, secondary RFAs are necessary. The present study was designed to analyze the dynamic change of nodular volume of benign thyroid tumors accessed using contrast-enhanced ultrasonography (CEUS) after RFA, and hopefully to offer evidence for time decision of secondary RFA.
methodsA total of 105 patients who received ultrasonography-guided RFA in the Department of Ultrasound, Chinese PLA General Hospital between April 2014 and August 2018 for benign thyroid nodule were enrolled in this retrospective study. Vt increase (regrowth) and vital volume (Vv) of thyroid nodule were followed up at 0, 1, 3, 6, 12, 24 and 36 months after RFA.
resultsA total of 105 nodules of 105 patients were enrolled in the present study, with a mean age of 46.70 ± 13.05 years, and 87 of them (82.9%) were female. The median follow up time was 25.1 months (12 months to 36 months). During the follow up, regrowth occurred in 43 cases, 95.35% of nodular regrowth occurred in 12 months after RFA, and the rate showed substantial consistency with that on the 36th month postoperatively (Kappa = 0.656).
conclusionsCEUS was an effective and safe tool to monitor volume change of benign thyroid nodules after RFA. The majority cases of regrowth occurred in 12 months after RFA, thus, the 12th month after RFA might be the optimal time for volume assessment to make the decision of secondary RFAs.
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