Evidence map›Paper›PMID 32664824›Full record

ArticleUnited European gastroenterology journal2020

The new simplified MARIA score applies beyond clinical trials: A suitable clinical practice tool for Crohn's disease that parallels a simple endoscopic index and fecal calprotectin.

Joana Roseira, Ana Rita Ventosa, Helena Tavares de Sousa, Jorge Brito

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Article in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Novel outcomes in inflammatory bowel disease.Journal of Crohn's & colitis · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joana RoseiraGastroenterology Department, Centro Hospitalar Universitário do Algarve, Portimão, Portugal.ORCID 0000-0002-5098-8729
Ana Rita VentosaABC - Algarve Biomedical Center, Portimão, Portugal.
Helena Tavares de SousaGastroenterology Department, Centro Hospitalar Universitário do Algarve, Portimão, Portugal.
Jorge BritoABC - Algarve Biomedical Center, Portimão, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA simplified magnetic resonance enterography (MRe) index (sMARIA) for Crohn's disease (CD) was recently developed and validated.

objectiveOur aims were (a) to assess sMARIA's accuracy in a sample other than the validation cohort; (b) to evaluate its correlation with a simpler endoscopy index (SES-CD) and fecal calprotectin (FC); and (c) to assess the need of an expert radiologist to reliably use sMARIA.

methodsPatients with CD who underwent MRe, ileocolonoscopy and FC within 2-4 weeks had their MRe retrospectively reviewed by two blinded raters. Disease activity was evaluated through sMARIA, SES-CD and FC. sMARIA's accuracy, indices correlation, and interrater reliability were assessed.

resultsIn total, 84 patients were included, comprising 420 intestinal segments evaluations. sMARIA ≥1 accurately identified segments with active disease (90% sensitivity, 98% specificity; area under the curve 0.94, 95% confidence interval (CI) 0.91-0.97;

conclusionsMARIA accurately measured CD activity using SES-CD as standard of reference, and exhibited high correlation with a simple endoscopic index and a biomarker. The interrater reliability between a radiology resident and an expert was excellent.

Indexed as

Magnetic Resonance ImagingAdultBiomarkersColonColonoscopyCrohn DiseaseFecesFemaleHumansIleumLeukocyte L1 Antigen ComplexMaleProspective StudiesRetrospective StudiesSeverity of Illness IndexYoung AdultBiomarkersLeukocyte L1 Antigen ComplexInflammatory Bowel DiseaseMagnetic Resonancemonitoring tools

Identifiers

PMID32664824
PMCPMC7724527

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.