Evidence map›Paper›PMID 32664560›Full record

ArticleMolecules (Basel, Switzerland)2020

Influence of Various Model Compounds on the Rheological Properties of Zein-Based Gels.

Agnese Gagliardi, Silvia Voci, Donatella Paolino, Massimo Fresta, Donato Cosco

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agnese GagliardiDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, Campus Universitario "S. Venuta", I-88100 Catanzaro, Italy.
Silvia VociDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "SVenuta", I-88100 Catanzaro, Italy.
Donatella PaolinoDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, Campus Universitario "S. Venuta", I-88100 Catanzaro, Italy.ORCID 0000-0002-5223-9879
Massimo FrestaDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "SVenuta", I-88100 Catanzaro, Italy.ORCID 0000-0001-8062-817X
Donato CoscoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "SVenuta", I-88100 Catanzaro, Italy.ORCID 0000-0002-4898-0365

Funding

Italian Ministry of University and Research PRIN2017, prot.n. 20173ZECCM_003
6 · The paper itself

Abstract

The controlled release of a compound entrapped in a biocompatible formulation is a sought-after goal in modern pharmaceutical technology. Zein is a hydrophobic protein which has several advantageous properties that make it suitable for use as a biocompatible and degradable material under physiological conditions. It is, therefore, proposed for different biomedical and pharmaceutical applications. In particular, due to its gelling properties, it can be used to form a polymeric network able to preserve biomolecules from harsh environments. The current study was designed to investigate the influence of different probes on the rheological properties of gels made up of zein, in order to characterize the systems as a function of the polymer concentration. Four model compounds characterized by different physico-chemical properties were entrapped in zein gels, and different behaviors (viscoelastic or pronounced solid-like characteristics) of the systems were observed. Zein-based gels showed various release profiles of the encapsulated compounds, suggesting that there are different interaction rates between the probes and the polymeric matrix.

Indexed as

GelsRheologyViscosityZeinGelsZeincontrolled releasegelspolymeric matrixprobesrheologyzein

Identifiers

PMID32664560
PMCPMC7397198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.