Evidence map›Paper›PMID 32664512›Full record

ArticleGenes2020

Genetic Variation in Complex Traits in Transgenic α-Synuclein Strains of

Yiru A Wang, Lisa van Sluijs, Yu Nie, Mark G Sterken, Simon C Harvey, Jan E Kammenga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yiru A WangLaboratory of Nematology, Wageningen University & Reseach, Droevendaalsesteeg 1, 6708PB Wageningen, NL, The Netherlands.
Lisa van SluijsLaboratory of Nematology, Wageningen University & Reseach, Droevendaalsesteeg 1, 6708PB Wageningen, NL, The Netherlands.ORCID 0000-0002-4692-0844
Yu NieBiomolecular Research Group, Canterbury Christ Church University, North Holmes Road, Canterbury CT1 1QU, UK.
Mark G SterkenLaboratory of Nematology, Wageningen University & Reseach, Droevendaalsesteeg 1, 6708PB Wageningen, NL, The Netherlands.
Simon C HarveyBiomolecular Research Group, Canterbury Christ Church University, North Holmes Road, Canterbury CT1 1QU, UK.
Jan E KammengaLaboratory of Nematology, Wageningen University & Reseach, Droevendaalsesteeg 1, 6708PB Wageningen, NL, The Netherlands.ORCID 0000-0003-4822-4436
Canterbury Christ Church University · GBWageningen University & Research · NL

Funding

Identification of natural variants that influence responses to ethanol in C. elegansR01AA026658 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI BETTINGER, JILL C, KAMMENGA, JAN · 2018 to 2022
$1.7M
NIAAA NIH HHS R01 AA026658
6 · The paper itself

Abstract

Different genetic backgrounds can modify the effect of mutated genes. Human α-synuclein (

Indexed as

Transcription, Geneticalpha-SynucleinAnimalsAnimals, Genetically ModifiedBacterial ProteinsBody SizeCaenorhabditis elegansDisease Models, AnimalGene Expression RegulationGenetic VariationGenomeHumansLuminescent ProteinsLysosomesMultifactorial InheritanceParkinson Diseasealpha-SynucleinBacterial ProteinsLuminescent Proteinsyellow fluorescent protein, BacteriaC. elegansgenetic backgroundprotein accumulationα-synuclein

Identifiers

PMID32664512
PMCPMC7397059
OpenAlexW3041921004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.