ReviewJournal of clinical medicine2020
Prevention of Prosthetic Joint Infection: From Traditional Approaches towards Quality Improvement and Data Mining.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05239312 (Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Periprosthetic joint infection as failure of containment: A causal and probabilistic framework.Journal of orthopaedic translation · 2026Article
- Microfluidic and lab-on-a-chip devices for detection and diagnosis of periprosthetic joint infections.Biomedical microdevices · 2025Review
- Temporal Patterns and Treatment Associations in Complications Following Hip Arthroplasty.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Machine learning to predict periprosthetic joint infections following primary total hip arthroplasty using a national database.Archives of orthopaedic and trauma surgery · 2025Article
- The application value and challenges of metagenomic next-generation sequencing in the diagnosis of periprosthetic joint infection after arthroplasty.Frontiers in medicine · 2025Review
- Preventive strategies to reduce the rate of periprosthetic infections in total joint arthroplasty; a comprehensive review.Archives of orthopaedic and trauma surgery · 2024Review
- New strontium-based coatings show activity against pathogenic bacteria in spine infection.Frontiers in bioengineering and biotechnology · 2024Article
- Periprosthetic joint infection caused by Haemophilus parainfluenzae. Case report and literature review.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023Review
- The Role of Single Positive Cultures in Presumed Aseptic Total Hip and Knee Revision Surgery-A Systematic Review of the Literature.Diagnostics (Basel, Switzerland) · 2023Review
- Prevalence of modifiable risk factors in primary elective arthroplasty and their association with infections.Acta orthopaedica · 2023Article
- Article
- Sonication of revised hip and knee prostheses detects occult infections, improves clinical outcomes and prevents re - revisions. A case series study.Infection prevention in practice · 2022Article
- Antimicrobial Peptides in the Battle against Orthopedic Implant-Related Infections: A Review.Pharmaceutics · 2021Review
- Bacterial profile and antimicrobial susceptibility patterns of isolates among patients diagnosed with surgical site infection at a tertiary teaching hospital in Ethiopia: a prospective cohort study.Annals of clinical microbiology and antimicrobials · 2021Article
- Intraoperative Bacterial Contamination and Activity of Different Antimicrobial Prophylaxis Regimens in Primary Knee and Hip Replacement.Antibiotics (Basel, Switzerland) · 2020Article
- Prosthetic Joint Infection: Updates on Prevention, Diagnosis and Therapy.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A projected increased use of total joint arthroplasties will naturally result in a related increase in the number of prosthetic joint infections (PJIs). Suppression of the local peri-implant immune response counters efforts to eradicate bacteria, allowing the formation of biofilms and compromising preventive measures taken in the operating room. For these reasons, the prevention of PJI should focus concurrently on the following targets: (i) identifying at-risk patients; (ii) reducing "bacterial load" perioperatively; (iii) creating an antibacterial/antibiofilm environment at the site of surgery; and (iv) stimulating the local immune response. Despite considerable recent progress made in experimental and clinical research, a large discrepancy persists between proposed and clinically implemented preventative strategies. The ultimate anti-infective strategy lies in an optimal combination of all preventative approaches into a single "clinical pack", applied rigorously in all settings involving prosthetic joint implantation. In addition, "anti-infective" implants might be a choice in patients who have an increased risk for PJI. However, further progress in the prevention of PJI is not imaginable without a close commitment to using quality improvement tools in combination with continual data mining, reflecting the efficacy of the preventative strategy in a particular clinical setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.