Evidence map›Paper›PMID 32664474›Full record

ArticleCancers2020

Cancer-Associated Substitutions in RNA Recognition Motifs of PUF60 and U2AF65 Reveal Residues Required for Correct Folding and 3' Splice-Site Selection.

Jana Kralovicova, Ivana Borovska, Monika Kubickova, Peter J Lukavsky, Igor Vorechovsky

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. RNA binding proteins in cardiovascular development and disease.Current topics in developmental biology · 2024
    Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Jana KralovicovaFaculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.
Ivana BorovskaInstitute of Molecular Physiology and Genetics, Center of Biosciences, Slovak Academy of Sciences, 840 05 Bratislava, Slovakia.
Monika KubickovaCEITEC, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0001-7680-9453
Peter J LukavskyCEITEC, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0003-2935-1579
Igor VorechovskyFaculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0002-6740-6502
Central European Institute of Technology – Masaryk University · CZSlovak Academy of Sciences · SKUniversity of Southampton · GB

Funding

Bloodwise 12060Marie Curie Career Integration Grannt PCIG14-GA-2013-630758SRDA APVV-18-0096VEGA 2-0057-18
6 · The paper itself

Abstract

U2AF65 (

Indexed as

3′ splice sitecancerdifferential scanning fluorimetrydriver mutationexon inclusionFunctional genomicsgel shift assaylariat branch pointleukemiamRNApre-mRNA splicingPUF60SF3B4U2AF2

Identifiers

PMID32664474
PMCPMC7408900
OpenAlexW3041782042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.