Evidence map›Paper›PMID 32664451›Full record

ArticleInternational journal of molecular sciences2020

A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice.

Tim Weigand, Florian Colbatzky, Tilman Pfeffer, Sven F Garbade, Kristina Klingbeil, Florian Colbatzky, Michael Becker, Johanna Zemva, Ruben Bulkescher, Robin Schürfeld and 11 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Dietary supplementation withAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  9. Review
  10. Article
  11. Antioxidants (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Anserine and Carnosine Induce HSP70-Dependent HAntioxidants (Basel, Switzerland) · 2022
    Article
  14. A Novel UPLC-MS/MS Method Identifies Organ-Specific Dipeptide Profiles.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Tim WeigandCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Florian ColbatzkyCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Tilman PfefferCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Sven F GarbadeCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Kristina KlingbeilCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Florian ColbatzkyNonclinical Drug Safety Germany, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany.ORCID 0000-0001-8987-1619
Michael BeckerDrug Metabolism & Pharmacokinetics Germany, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany.
Johanna ZemvaInternal Medicine I and Clinical Chemistry, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Ruben BulkescherInternal Medicine I and Clinical Chemistry, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Robin SchürfeldCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Christian ThielCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Nadine VolkTissue Bank of the National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
David ReussNeuropathology, University of Heidelberg, 69120 Heidelberg, Germany.
Georg F HoffmannCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-6593-896X
Marc FreichelInstitute of Pharmacology, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0003-1387-2636
Markus HeckerDepartment of Cardiovascular Physiology, University of Heidelberg, 69120 Heidelberg, Germany.
Tanja PothCenter for Model System and Comparative Pathology (CMCP), Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Thomas FlemingInternal Medicine I and Clinical Chemistry, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Gernot PoschetCentre for Organismal Studies (COS), University of Heidelberg, 69120 Heidelberg, Germany.
Claus P SchmittCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Verena PetersCentre for Paediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-4649-0848
Heidelberg University · DEBoehringer Ingelheim (Germany) · DENational Center for Tumor Diseases · DE

Funding

Deutsche Forschungsgemeinschaft SFB1118
6 · The paper itself

Abstract

Carnosinase 1 (CN1) is encoded by the

Indexed as

Amino AcidsAnimalsAnserineBlood GlucoseCarnosineDiabetic NephropathiesDipeptidasesFemaleGlucoseHSP70 Heat-Shock ProteinsInsulinKidneyMaleMiceMice, Inbred C57BLMice, KnockoutAmino AcidsAnserineBlood GlucoseCarnosineDipeptidasesGlucoseHSP70 Heat-Shock ProteinsInsulinRNA, Messengeranserinecarnosinase 1carnosineCN1Cndp1glucose homeostasiskidney

Identifiers

PMID32664451
PMCPMC7402351
OpenAlexW3040868279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.