Evidence map›Paper›PMID 32664422›Full record

SynthesisBiomolecules2020

Defensins of Grasses: A Systematic Review.

Tatyana I Odintsova, Marina P Slezina, Ekaterina A Istomina

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2026
    Article
  2. Article
  3. Review
  4. Antifungal Peptides SmAPAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Complex of Defense Polypeptides of Wheatgrass (Plants (Basel, Switzerland) · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Insights of theJournal of fungi (Basel, Switzerland) · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tatyana I OdintsovaLaboratory of Molecular-Genetic Bases of Plant Immunity, Vavilov Institute of General Genetics RAS, 119333 Moscow, Russia.ORCID 0000-0002-5563-9755
Marina P SlezinaLaboratory of Molecular-Genetic Bases of Plant Immunity, Vavilov Institute of General Genetics RAS, 119333 Moscow, Russia.
Ekaterina A IstominaLaboratory of Molecular-Genetic Bases of Plant Immunity, Vavilov Institute of General Genetics RAS, 119333 Moscow, Russia.ORCID 0000-0001-6426-6009
Vavilov Institute of General Genetics · RU

Funding

Russian Science Foundation 16-16-00032
6 · The paper itself

Abstract

The grass family (Poaceae) is one of the largest families of flowering plants, growing in all climatic zones of all continents, which includes species of exceptional economic importance. The high adaptability of grasses to adverse environmental factors implies the existence of efficient resistance mechanisms that involve the production of antimicrobial peptides (AMPs). Of plant AMPs, defensins represent one of the largest and best-studied families. Although wheat and barley seed γ-thionins were the first defensins isolated from plants, the functional characterization of grass defensins is still in its infancy. In this review, we summarize the current knowledge of the characterized defensins from cultivated and selected wild-growing grasses. For each species, isolation of defensins or production by heterologous expression, peptide structure, biological activity, and structure-function relationship are described, along with the gene expression data. We also provide our results on in silico mining of defensin-like sequences in the genomes of all described grass species and discuss their potential functions. The data presented will form the basis for elucidation of the mode of action of grass defensins and high adaptability of grasses to environmental stress and will provide novel potent molecules for practical use in medicine and agriculture.

Indexed as

DefensinsDisease ResistanceGene Expression Regulation, PlantModels, MolecularPlant ProteinsPoaceaeProtein ConformationStructure-Activity RelationshipDefensinsPlant Proteins3D structure modelingantimicrobial peptides (AMPs)defensinsin silico miningplant immunityPoaceae

Identifiers

PMID32664422
PMCPMC7407236
OpenAlexW3040765619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.