Evidence map›Paper›PMID 32664411›Full record

ArticleVaccines2020

Response of Sport Horses to Different Formulations of Equine Influenza Vaccine.

Johanna Entenfellner, Jacinta Gahan, Marie Garvey, Cathal Walsh, Monica Venner, Ann Cullinane

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. AAnimals : an open access journal from MDPI · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Johanna EntenfellnerSchool of Veterinary Medicine, Bischofsholer Damm 15, 30173 Hannover, Germany.
Jacinta GahanIrish Equine Centre, Johnstown, Naas, Co. Kildare, W91 RH93 Johnstown, Ireland.
Marie GarveyIrish Equine Centre, Johnstown, Naas, Co. Kildare, W91 RH93 Johnstown, Ireland.
Cathal WalshDepartment of Mathematics and Statistics, University of Limerick, V94 T9PX Limerick, Ireland.ORCID 0000-0001-6599-9562
Monica VennerPferdeklinik Destedt GmbH, Destedt, Trift 4, 38162 Cremlingen, Germany.ORCID 0000-0002-1062-9406
Ann CullinaneIrish Equine Centre, Johnstown, Naas, Co. Kildare, W91 RH93 Johnstown, Ireland.
Irish Equine Centre · IEUniversity of Limerick · IEUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

Department of Agriculture, Food and the Marine, Ireland DAFM_IEC_OIE
6 · The paper itself

Abstract

The international governing body of equestrian sports requires that horses be vaccinated against equine influenza within 6 months and 21 days of competing. The aim of this study was to compare the antibody response of young sport horses to six-monthly booster vaccination with equine influenza vaccines of different formulations. An inactivated vaccine was allocated to 35 horses and subunit and recombinant vaccines were allocated to 34 horses each. After vaccination, all horses were monitored for evidence of adverse reactions. Whole blood samples were collected at the time of vaccination and on nine occasions up to six months and 21 days post vaccination. Antibodies against equine influenza were measured by single radial haemolysis. Transient fever and injection site reactions were observed in several horses vaccinated with each vaccine. Only two horses failed to seroconvert post booster vaccination but there was a delayed response to the recombinant vaccine. The antibody response to the recombinant vaccine was lower than that induced by the whole-inactivated and subunit vaccines up to three months post vaccination. Thereafter, there was no significant difference. By six months post vaccination, the majority of horses in all three groups were clinically but not virologically protected. There was minimal decline in antibody titres within the 21-day grace period.

Indexed as

antibodyequine influenzainactivatedreactogenicityrecombinant vaccinessport horsesubunit

Identifiers

PMID32664411
PMCPMC7563521
OpenAlexW3041474017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.