ReviewNutrients2020
Magnesium Sulfate-Rich Natural Mineral Waters in the Treatment of Functional Constipation-A Review.
Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Daily consumption of sulfate- and magnesium-rich mineral water enhances bowel function in adults with chronic constipation: a randomized double-blind real-world trial.Frontiers in nutrition · 2026Trial
- Combined anti-inflammatory and laxative effect of mango kernels-based effervescent suppositories loaded with (multi)metallic nanoparticles synthesized using ash of plantain peels and gel of Aloe vera.Drug delivery and translational research · 2026Article
- Hydration Meets Regulation: Insights into Bicarbonate Mineral Water and Acid-Base Balance.Nutrients · 2025Review
- A new type of ultrasonic water alleviates constipation with favorable safety.Frontiers in toxicology · 2025Article
- Association between dietary vitamin B2 intake and constipation: a nationwide cross-sectional study.Frontiers in medicine · 2025Article
- Article
- The association between dietary vitamin B1 intake and constipation: a population-based study.BMC gastroenterology · 2024Article
- Association between dietary vitamin E intake and constipation: NHANES 2005-2010.Frontiers in nutrition · 2024Article
- Exploring Pharmacological Treatments for Chronic Idiopathic Constipation in Adults: A Look Back to the Future.Journal of clinical medicine · 2023Review
- Incidence, risk factors, and therapeutic management of equine colic in Lamongan, Indonesia.Veterinary world · 2023Article
- Saudi Experts Consensus on Diagnosis and Management of Pediatric Functional Constipation.Pediatric gastroenterology, hepatology & nutrition · 2022Review
- Association of Dietary Energy Intake With Constipation Among Men and Women: Results From the National Health and Nutrition Examination Survey.Frontiers in nutrition · 2022Article
- Fluid intake and urinary osmolality in pediatric patients with functional constipation.European journal of nutrition · 2021Article
- Association of dietary magnesium intake with chronic constipation among US adults: Evidence from the National Health and Nutrition Examination Survey.Food science & nutrition · 2021Article
- Chronic Constipation: Is a Nutritional Approach Reasonable?Nutrients · 2021Review
- Current Overview on Clinical Management of Chronic Constipation.Journal of clinical medicine · 2021Review
- Effects of Sodium Chloride-Rich Mineral Water on Intestinal Epithelium. Experimental Study.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional constipation (FC) is a chronic constipation for which no physiological, anatomical or iatrogenic origin can be evidenced. This condition has a high impact on a patient's quality of life and healthcare costs. Since FC is frequently associated with low physical activity and a diet low in fiber and/or water, first-line recommendations focus on sufficient activity, and sufficient fiber and water intake. In case of inefficacy of these measures, numerous drug treatments are available, either over the counter or on prescription. Magnesium sulfate has a long history in the treatment of FC, and magnesium sulfate-rich mineral waters have been used for centuries for their laxative properties. The laxative effect of magnesium and sulfate has since been widely demonstrated. Nevertheless, it appears that no clinical studies aiming at demonstrating their efficacy in FC had been conducted before the 21st century. In this paper, we reviewed the clinical data reporting the efficacy of magnesium sulfate-rich natural mineral waters. In view of their reported efficacy and safety, magnesium sulfate-rich natural mineral waters may represent a natural treatment for FC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.