Evidence map›Paper›PMID 32664312›Full record

ArticleAnimals : an open access journal from MDPI2020

TRPV4 Increases the Expression of Tight Junction Protein-Encoding Genes via XBP1 in Mammary Epithelial Cells.

Md Aminul Islam, Moeko Mizusawa, Mst Mamuna Sharmin, Satoko Hayashi, Shinichi Yonekura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Md Aminul IslamDepartment of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University, Minamiminowa, Kamiina 399-4598, Nagano, Japan.
Moeko MizusawaDepartment of Biomedical Engineering, Graduate School of Science and Technology, Shinshu University, Minamiminowa, Kamiina 399-4598, Nagano, Japan.
Mst Mamuna SharminDepartment of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University, Minamiminowa, Kamiina 399-4598, Nagano, Japan.
Satoko HayashiDepartment of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University, Minamiminowa, Kamiina 399-4598, Nagano, Japan.
Shinichi YonekuraDepartment of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University, Minamiminowa, Kamiina 399-4598, Nagano, Japan.
Shinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild heat stress (39 °C-40 °C) can positively regulate cell proliferation and differentiation. Indeed, mild heat treatment at 39 °C enhances the less-permeable tight junctions (TJs) formation and milk production in mammary epithelial cells. However, the molecular mechanisms of this response have not yet been delineated. In this study, the involvement of temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) in the increase of

Indexed as

HC11 mouse mammary epithelial cellmammary gland developmentTRPV4UPR

Identifiers

PMID32664312
PMCPMC7401603
OpenAlexW3041616987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.