Evidence map›Paper›PMID 32664140›Full record

ArticleMedicine2020

Tigecycline in the treatment of fulminant Mycoplasma pneumoniae pneumonia non-responsive to azithromycin and fluoroquinolone: A case report.

Xin Yuan, Jie Liu, Changqing Bai, Wenkai Niu, Jingjing Wang, Puyuan Li, Huiying Liu, Yuan Luo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Walking Pneumonia - Not Always so Timid. A Case of Severe ARDS Due to Fulminant Mycoplasma Pneumonia.Journal of community hospital internal medicine perspectives · 2025
    Article
  4. Article
  5. [Macrolide-resistant Mycoplasma pneumoniae: Do we know the situation in Europe?]Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Review
  6. Article
  7. Case Report: Clinical Analysis of FulminantFrontiers in pediatrics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xin YuanDepartment of Respiratory and Critical Care Medicine, the Fifth Medical Centre of Chinese PLA General Hospital, Beijing.
Jie LiuDepartment of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya.
Changqing BaiDepartment of Respiratory and Critical Care Medicine, the Fifth Medical Centre of Chinese PLA General Hospital, Beijing.
Wenkai NiuDepartment of Respiratory and Critical Care Medicine, the Fifth Medical Centre of Chinese PLA General Hospital, Beijing.
Jingjing WangDepartment of Respiratory and Critical Care Medicine, the Fifth Medical Centre of Chinese PLA General Hospital, Beijing.
Puyuan LiDepartment of Respiratory and Critical Care Medicine, the Fifth Medical Centre of Chinese PLA General Hospital, Beijing.
Huiying LiuDepartment of Respiratory and Critical Care Medicine, the Fifth Medical Centre of Chinese PLA General Hospital, Beijing.
Yuan LuoInstitute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, China.
Chinese PLA General Hospital · CNAcademy of Military Medical Sciences · CNHainan General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleFulminant macrolide-resistant Mycoplasma pneumoniae pneumonia (MPP) has seldom been reported, and cases of MPP usually show rapid improvement after fluoroquinolones or tetracyclines addition. The purpose of this case report is to highlight the importance of proper selection of antibiotics for treatment of severe MPP and increase awareness concerning the emergence of fluoroquinolone-resistant MPP. PATIENT CONCERNS: A case of severe life-threatening pneumonia in a 26-year-old man with high fever and cough was non-responsive to azithromycin and fluoroquinolones. DIAGNOSES: The patient was diagnosed with MPP based on the test results of bronchoalveolar lavage using real-time quantitative PCR method.

interventionsTigecycline was given to the patient after azithromycin and fluoroquinolones failed. OUTCOMES: The patients fever subsided within the first day of tigecycline therapy. He showed rapid symptom resolution and improvement in lung infiltration after 4 days of tigecycline therapy. LESSONS: The case suggests that fulminant MPP should be timely treated with proper antibiotics, and the possible emergence of fluoroquinolone-resistant MPP should be of concern.

Indexed as

Acute DiseaseAdultAnti-Bacterial AgentsAzithromycinBrochothrixDrug Resistance, BacterialFluoroquinolonesHumansMaleMycoplasma pneumoniaePneumonia, MycoplasmaTigecyclineTomography, X-Ray ComputedAnti-Bacterial AgentsAzithromycinFluoroquinolonesTigecycline

Identifiers

PMID32664140
PMCPMC7360219
OpenAlexW3041695626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.