ArticleJournal of affective disorders2020
Electroconvulsive therapy (ECT) for moderate-severity major depression among the elderly: Data from the pride study.
Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Adherence to clinical practice guidelines for using electroconvulsive therapy in elderly depressive patients.BMC psychiatry · 2024Article
- Treatment-Resistant Depression in Older Adults.The New England journal of medicine · 2024Review
- Trajectories of Efficacy and Cognitive Function During Electroconvulsive Therapy Course in Young Adults with Treatment-Resistant Depression.Neuropsychiatric disease and treatment · 2023Article
- Recent advances in electroconvulsive therapy in clinical practice and research.Faculty reviews · 2023Review
- The Use of ECT in the Elderly-Looking Beyond Depression.Current psychiatry reports · 2022Review
- Correlating electroconvulsive therapy response to electroencephalographic markers: Study protocol.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundElectroconvulsive therapy (ECT) is usually reserved for treatment of severe major depressive disorder (MDD), but may be equally effective in the treatment of moderate-severity MDD. This possibility, however, has only been studied to a very limited extent. We therefore investigated the efficacy of ECT after stratifying patients into severe MDD and moderate-severity MDD.
methodsWe used data from the Prolonging Remission in Depressed Elderly (PRIDE) study, in which 240 patients (≥60 years) with MDD were treated with right unilateral ultrabrief pulse ECT, combined with venlafaxine. We used the six-item core depression subscale (HAM-D
resultsAmong the participants with severe MDD and moderate-severity MDD, the mean change in the HAM-D LIMITATIONS: The PRIDE study was not designed to address this research question.
conclusionsECT combined with venlafaxine appears to be an effective treatment for moderate-severity MDD. It may be appropriate to expand the indications for ECT to include patients with moderate-severity MDD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.