Evidence map›Paper›PMID 32663724›Full record

ArticleVeterinary immunology and immunopathology2020

Anatomical distribution of respiratory tract leukocyte cell subsets in neonatal calves.

Quinn K Kolar, Lindsey A Waddell, Anna Raper, Mara S Rocchi, Darren J Shaw, Alexander Corbishley, Jayne C Hope

Open access · greenAbstract read
In one paragraph

Article in Veterinary immunology and immunopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Quinn K KolarThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, EH259RG, United Kingdom.
Lindsey A WaddellThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, EH259RG, United Kingdom.
Anna RaperThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, EH259RG, United Kingdom.
Mara S RocchiMoredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, EH260PZ, United Kingdom.
Darren J ShawThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, EH259RG, United Kingdom.
Alexander CorbishleyThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, EH259RG, United Kingdom.
Jayne C HopeThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, EH259RG, United Kingdom. Electronic address: jayne.hope@roslin.ed.ac.uk.
Roslin Institute · GBMoredun Research Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal calves are highly susceptible to a number of diseases including those that infect via the mucosal surfaces of the respiratory and gastrointestinal tracts. In order to determine appropriate vaccine design and delivery systems, or to identify suitable immunostimulatory methods to combat these infections, a detailed understanding of the immune cell populations present at clinically relevant sites is key. Few studies have assessed the immune cell composition of the neonatal calf lung and comparisons with circulating immune cells in the blood are lacking. We describe immune cell populations present in the peripheral blood, bronchoalveolar lavage (BAL) fluid and lung tissue of young disease-free calves. Flow cytometric analysis revealed significant differences in cell subset distribution between the peripheral blood and respiratory tract, and between compartments within the respiratory tract. Notably, whereas WC1

Indexed as

AnimalsAnimals, NewbornBronchoalveolar Lavage FluidCattleCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFlow CytometryKiller Cells, NaturalLungLymphocyte CountMaleRespiratory SystemT-Lymphocyte SubsetsBovine respiratory disease complex (BRDC)Myeloid cellsNatural killer cellsNeonatal immunityRespiratory tract

Identifiers

PMID32663724
PMCPMC7331561
OpenAlexW3040644184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.