ArticleGenomics, proteomics & bioinformatics2020
Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters.
Article in Genomics, proteomics & bioinformatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed.
- On Rooting and Dating Viral Trees With a Changing Evolutionary Rate Following Host-Switching.Genome biology and evolution · 2025Article
- Rapid identification of full-length genome and tracing variations of monkeypox virus in clinical specimens based on mNGS and amplicon sequencing.Virologica Sinica · 2024Article
- Genomic and epidemiological perspectives on the first local sporadic cases of Mpox in China.Emerging microbes & infections · 2023Article
- RCoV19: A One-stop Hub for SARS-CoV-2 Genome Data Integration, Variant Monitoring, and Risk Pre-warning.Genomics, proteomics & bioinformatics · 2023Article
- Reconstructing early transmission networks of SARS-CoV-2 using a genomic mutation model.Zoological research · 2023Article
- Rooting and Dating Large SARS-CoV-2 Trees by Modeling Evolutionary Rate as a Function of Time.Viruses · 2023Article
- Article
- Ongoing Positive Selection Drives the Evolution of SARS-CoV-2 Genomes.Genomics, proteomics & bioinformatics · 2022Article
- Using multiple sampling strategies to estimate SARS-CoV-2 epidemiological parameters from genomic sequencing data.Nature communications · 2022Article
- Variant-Specific Analysis Reveals a Novel Long-Range RNA-RNA Interaction in SARS-CoV-2 Orf1a.International journal of molecular sciences · 2022Article
- Pinpointing the animal origins of SARS-CoV-2: a genomic approach.Journal of genetics and genomics = Yi chuan xue bao · 2022Article
- SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations.Pathogens (Basel, Switzerland) · 2022Article
- SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes.Microbiology spectrum · 2022Article
- End-point RT-PCR based on a conservation landscape for SARS-COV-2 detection.Scientific reports · 2022Article
- Mutation signatures inform the natural host of SARS-CoV-2.National science review · 2022Article
- Population Genomics Approaches for Genetic Characterization of SARS-CoV-2 Lineages.Frontiers in medicine · 2022Article
- Both simulation and sequencing data reveal coinfections with multiple SARS-CoV-2 variants in the COVID-19 pandemic.Computational and structural biotechnology journal · 2022Article
- Identification and characterization of SARS-CoV-2 clusters in the EU/EEA in the first pandemic wave: additional elements to trace the route of the virus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021Article
- Data-driven identification of SARS-CoV-2 subpopulations using PhenoGraph and binary-coded genomic data.Briefings in bioinformatics · 2021Article
- Phylogenomics and population genomics of SARS-CoV-2 in Mexico during the pre-vaccination stage reveals variants of interest B.1.1.28.4 and B.1.1.222 or B.1.1.519 and the nucleocapsid mutation S194L associated with symptoms.Microbial genomics · 2021Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel RNA virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for the ongoing outbreak of coronavirus disease 2019 (COVID-19). Population genetic analysis could be useful for investigating the origin and evolutionary dynamics of COVID-19. However, due to extensive sampling bias and existence of infection clusters during the epidemic spread, direct applications of existing approaches can lead to biased parameter estimations and data misinterpretation. In this study, we first present robust estimator for the time to the most recent common ancestor (TMRCA) and the mutation rate, and then apply the approach to analyze 12,909 genomic sequences of SARS-CoV-2. The mutation rate is inferred to be 8.69 × 10
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.