ArticleJournal of gastroenterology and hepatology2021
Long-term outcomes after endoscopic submucosal dissection for differentiated-type early gastric cancer that fulfilled expanded indication criteria: A prospective cohort study.
Article in Journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Article
- Discrepancies between preoperative assessment and final pathological criteria in early gastric cancer.World journal of gastrointestinal oncology · 2026Article
- Assessment of early gastric cancer visibility in deep-learning-based virtual indigo carmine chromoendoscopy (with video).Endoscopy international open · 2026Article
- A multicenter retrospective study: risk factors and nomogram construction for pathological escalation of gastric low-grade intraepithelial neoplasia.Frontiers in medicine · 2026Article
- Multidimensional decision support by artificial intelligence across the full workflow of endoscopic submucosal dissection for early gastric cancer.Frontiers in oncology · 2026Review
- Machine-Learning Prediction of Bleeding After Endoscopic Submucosal Dissection for Early Gastric Cancer: A Multicenter Study.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Long-term outcome of regional cooperation pathway after endoscopic submucosal dissection for early detection of new gastric cancer.Surgical endoscopy · 2024Article
- A machine learning model for predicting the lymph node metastasis of early gastric cancer not meeting the endoscopic curability criteria.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024Article
- Risk factors for pathological upgrading and noncurative resection in patients with gastric mucosal lesions after endoscopic submucosal dissection.BMC gastroenterology · 2024Article
- Diagnostic performance of deep-learning-based virtual chromoendoscopy in gastric neoplasms.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024Article
- Article
- Editorial article to: Animal experimental study on magnetic anchor technique-assisted endoscopic submucosal dissection of early gastric cancer.World journal of gastrointestinal endoscopy · 2024Article
- Risk assessment of metachronous gastric cancer after endoscopic submucosal dissection based on endoscopic intestinal metaplasia.JGH open : an open access journal of gastroenterology and hepatology · 2023Article
- Endoscopic resection of early gastric cancer.Journal of exercise rehabilitation · 2023Review
- Clinical and endoscopic features of metachronous gastric cancer with possible lymph node metastasis after endoscopic submucosal dissection and Helicobacter pylori eradication.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023Article
- Review
- A Prediction Model Based on the Risk Factors Associated with Pathological Upgrading in Patients with Early-Stage Gastric Neoplasms Diagnosed by Endoscopic Forceps Biopsy.Gut and liver · 2023Article
- Follow-up after endoscopic resection for early gastric cancer in 3 French referral centers.iGIE : innovation, investigation and insights · 2022Article
- Feasibility of same-day discharge following endoscopic submucosal dissection for esophageal or gastric early cancer.World journal of gastroenterology · 2022Article
- Construction and analysis of an ulcer risk prediction model after endoscopic submucosal dissection for early gastric cancer.World journal of gastrointestinal oncology · 2022Article
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25 authors.
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Abstract
BACKGROUND AND
aimEndoscopic resection for early gastric cancer (EGC) is widely performed. However, there is still a paucity of strong evidence regarding long-term outcomes after endoscopic submucosal dissection (ESD) for the expanded indication criteria of the Japanese guidelines (ver. 2010).
methodsEndoscopic submucosal dissection was performed in patients with EGC that met the expanded indication criteria: (i) cT1a, differentiated-type EGC of 2 to 5 cm, ulcer negative or (ii) cT1a, differentiated-type EGC of ≤3 cm, ulcer positive. Patients whose pathological examination fulfilled the curative resection criteria were then enrolled in this cohort study: negative vertical margin, negative lymphovascular invasion, and (i) pT1a, differentiated-type, and ulcer negative; (ii) pT1a, differentiated-type, ≤3 cm, and ulcer positive; or (iii) pT1b1 (<500-μm submucosal invasion), differentiated-type, and ≤3 cm. Patients with only a positive horizontal margin as a noncurative factor were included for follow-up.
resultsFrom September 2003 to February 2012, a total of 356 patients underwent ESD, and 214 were enrolled in the survival analysis. One hundred twenty patients (56%) had >2 cm in diameter and ulcer-negative lesions, and 94 (44%) had ≤3 cm and ulcer-positive lesions. The vital status at 5 years after ESD was confirmed in all (100%) patients. No local or metastatic recurrence was detected; however, 26 metachronous gastric cancers developed, and 1 patient died of metachronous gastric cancer. The 5-year disease-specific and overall survival rates were 99.5% (95% confidence interval [CI], 97.2%-100%) and 93.9% (95% CI, 89.8%-96.4%), respectively.
conclusionESD for EGC that fulfills the expanded criteria is feasible and shows favorable long-term outcomes.
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