Evidence map›Paper›PMID 32662543›Full record

ArticleNMR in biomedicine2020

Pyruvate-lactate exchange and glucose uptake in human prostate cancer cell models. A study in xenografts and suspensions by hyperpolarized [1-

Frits H A van Heijster, Sandra Heskamp, Vincent Breukels, Andor Veltien, Gerben M Franssen, Kees C F J Jansen, Otto C Boerman, Jack A Schalken, Tom W J Scheenen, Arend Heerschap

Open access · hybridAbstract read
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Stable electron-irradiated [1-Science advances · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Frits H A van HeijsterDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-0814-5189
Sandra HeskampDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Vincent BreukelsDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Andor VeltienDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Gerben M FranssenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Kees C F J JansenDepartment of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.
Otto C BoermanDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Jack A SchalkenDepartment of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.
Tom W J ScheenenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Arend HeerschapDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-9930-4562
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reprogramming of energy metabolism in the development of prostate cancer can be exploited for a better diagnosis and treatment of the disease. The goal of this study was to determine whether differences in glucose and pyruvate metabolism of human prostate cancer cells with dissimilar aggressivenesses can be detected using hyperpolarized [1-

Indexed as

Carbon-13 Magnetic Resonance SpectroscopyPositron-Emission TomographyXenograft Model Antitumor AssaysAnimalsCell Line, TumorEnergy MetabolismFluorodeoxyglucose F18GlucoseHumansKineticsLactatesMaleMice, Inbred BALB CProstatic NeoplasmsPyruvic AcidTissue DistributionFluorodeoxyglucose F18GlucoseLactatesPyruvic Acid13C MRS18F[FDG]hyperpolarizationPETprostate cellspyruvate, xenografts

Identifiers

PMID32662543
PMCPMC7507209
OpenAlexW3042609187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.