ArticleMovement disorders : official journal of the Movement Disorder Society2020
Visual Impairment Is More Common in Parkinson's Disease and Is a Risk Factor for Poor Health Outcomes.
Article in Movement disorders : official journal of the Movement Disorder Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- Bright light therapy in Parkinson's disease: a pilot study on visual pathway improvements.BMC psychiatry · 2025Trial
- Oculomotor Dance Task: Implications for Audio-Visual-Cued Spatial Learning.Vision (Basel, Switzerland) · 2026Article
- How to advance the pharmacological management of cognitive impairment in Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Retinal Pathology and Synucleinopathy in the Visual Pathway of α-Synuclein Preformed Fibril Mouse Model of Parkinson's Disease.Brain and behavior · 2026Article
- Evidence for divergent cortical organisation in Parkinson's disease and Lewy Body Dementia.Nature communications · 2025Article
- Neural basis of dysexecutive and visuospatial impairments in Parkinson's disease with MCI: a task-based fNIRS study.NPJ Parkinson's disease · 2025Article
- Redefining Non-Motor Symptoms in Parkinson's Disease.Journal of personalized medicine · 2025Review
- Keeping an eye on Parkinson's disease: color vision and outer retinal thickness as simple and non-invasive biomarkers.Journal of neurology · 2025Review
- Regional cerebral cholinergic vesicular transporter correlates of visual contrast sensitivity in Parkinson's disease: Implications for visual and cognitive function.Parkinsonism & related disorders · 2025Article
- Convergent reductions in interhemispheric functional, structural and callosal connectivity in Parkinson's disease.Frontiers in aging neuroscience · 2025Article
- Neuroimaging and fluid biomarkers in Parkinson's disease in an era of targeted interventions.Nature communications · 2024Review
- Perceptions of vision care following neurological impairment: a qualitative study.BMC health services research · 2024Article
- Cataract surgery utilization in Parkinson's disease: the english longitudinal survey on ageing.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Incidence and risk factors of age-related macular degeneration in patients with Parkinson's disease: a population-based study.Frontiers in aging neuroscience · 2024Article
- Mendelian randomization reveals association between retinal thickness and non-motor symptoms of Parkinson's disease.NPJ Parkinson's disease · 2023Article
- Visual Dysfunction and Occupational Performance in Persons With Parkinson's Disease.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2023Article
- Visual dysfunction is a better predictor than retinal thickness for dementia in Parkinson's disease.Journal of neurology, neurosurgery, and psychiatry · 2023Article
- Clinical trials for cognition in Parkinson's disease: Where are we and how can we do better?Parkinsonism & related disorders · 2023Review
- Structural and functional changes in the retina in Parkinson's disease.Journal of neurology, neurosurgery, and psychiatry · 2023Review
- Acute Visual Impairment in a Patient with Parkinson's Disease after Successful Bilateral Subthalamic Nucleus Deep Brain Stimulation with Low-Dose Levodopa: A Case Report.Brain sciences · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundVisual impairment is associated with hip fracture, depression, anxiety, and dementia in the general population, and many causes of visual impairment are preventable or treatable with early detection. However, the prevalence, outcomes, and healthcare utilization patterns associated with visual impairment have not been examined in Parkinson's disease (PD).
methodsWe performed a cross-sectional analysis of all Medicare beneficiaries with complete data in 2014 and longitudinal analysis of beneficiaries with PD from 2010 to 2014. We used diagnosis and procedure codes to identify PD, visual impairment, eye exams, hip fracture, and neuropsychiatric disorders. We compared the prevalence of visual impairment using logistic regression and used Cox proportional hazards regression to examine visual impairment and incident hip fracture, depression, anxiety, dementia, and death. We also examined the frequency of eye exams in PD using repeated-measures logistic regression.
resultsAmong 26,209,997 Medicare beneficiaries in 2014, visual impairment was significantly more prevalent in PD (1.7%) than non-PD (0.71%) (adjusted odds ratio, 1.60; 95% confidence interval [CI], 1.56-1.65). In a longitudinal cohort of 542,224 Medicare beneficiaries with PD, less than 60% had a yearly eye exam. Visual impairment associated with increased hazard of depression (hazard ratio [HR], 1.23; 95% CI, 1.14-1.32), anxiety (HR, 1.34; 95% CI, 1.24-1.43), dementia (HR, 1.28; 95% CI, 1.21-1.36), and death (HR, 1.49; 95% CI, 1.44-1.55).
conclusionVisual impairment is more common in PD than the general population and is associated with negative PD-related outcomes. Understanding the mechanisms for these relationships is important for guiding future interventions to improve health outcomes in PD. © 2020 International Parkinson and Movement Disorder Society.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.