Evidence map›Paper›PMID 32662244›Full record

ArticleAging cell2020

Autophagy regulates the localization and degradation of p16

Philip R Coryell, Supreet K Goraya, Katherine A Griffin, Margaret A Redick, Samuel R Sisk, Jeremy E Purvis

Open access · goldAbstract read
In one paragraph

Article in Aging cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 39 citations in OpenAlex.

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  14. A Barth Syndrome Patient-DerivedInternational journal of molecular sciences · 2024
    Article
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  16. Review
  17. Article
  18. Adenosine A2A receptor activation reduces chondrocyte senescence.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Philip R CoryellDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0001-9991-1987
Supreet K GorayaDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Katherine A GriffinDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Margaret A RedickDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-1901-458X
Samuel R SiskDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jeremy E PurvisDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · US

Funding

UG Support Administrative Supplement: Computational Models of the Human Cell Cycle to Reveal Disease Mechanism and Inform TreatmentR01GM138834 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Jeremy Purvis · 2020 to 2026
$2.7M
Controlling Stem Cell Fate through Computational ModelingDP2HD091800 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PURVIS, JEREMY · 2016 to 2018
$2.3M
Dynamics of cellular senescence in single human cells Admin SupplementR00GM102372 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PURVIS, JEREMY · 2013 to 2015
$886k
NICHD NIH HHS DP2 HD091800NIGMS NIH HHS R00 GM102372NIGMS NIH HHS R01 GM138834NIH HHS DP2-HD091800NIH HHS R00-GM102372NIH HHS T32-GM007092D
6 · The paper itself

Abstract

The tumor suppressor protein p16

Indexed as

AutophagyCyclin-Dependent Kinase Inhibitor p16HumansLysosomesCyclin-Dependent Kinase Inhibitor p16autophagyInk4alysosomesp16

Identifiers

PMID32662244
PMCPMC7370706
OpenAlexW3043375718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.