Evidence map›Paper›PMID 32662148›Full record

ArticleJournal of the science of food and agriculture2021

Cultured beef: from small biopsy to substantial quantity.

Lea Melzener, Karin E Verzijden, A Jasmin Buijs, Mark J Post, Joshua E Flack

Open access · hybridAbstract read
In one paragraph

Article in Journal of the science of food and agriculture, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 108 citations in OpenAlex.

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  8. Scaling Cultured Meat: Challenges and Solutions for Affordable Mass Production.Comprehensive reviews in food science and food safety · 2025
    Review
  9. Article
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  12. Cultivated meat microbiological safety considerations and practices.Comprehensive reviews in food science and food safety · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lea MelzenerMosa Meat B.V., Maastricht, Netherlands.
Karin E VerzijdenAxon Lawyers, Amsterdam, Netherlands.
A Jasmin BuijsAxon Lawyers, Amsterdam, Netherlands.
Mark J PostMosa Meat B.V., Maastricht, Netherlands.
Joshua E FlackMosa Meat B.V., Maastricht, Netherlands.ORCID https://orcid.org/0000-0003-4052-3909
Maastricht University · NLLawyers' Committee for Civil Rights Under Law · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cultured meat is an emerging technology with the potential to solve huge challenges related to the environmental, ethical, and health implications of conventional meat production. Establishing the basic science of cultured meat has been the primary focus of the last decade but it is now feasible that cultured meat products will enter the market within the next 3 to 4 years. This proximity to market introduction demands an evaluation of aspects of the cultured meat production process that have not yet been outlined or discussed in significant detail. For example, one technological approach for the production of cultured meat uses adult muscle stem cells, the limited proliferative capacity of which necessitates repeated collection of tissue samples via biopsies of living donor animals. The selection of donor animals and the details of biopsy processes must be optimized, as this is a key bottleneck in the cultured meat production process. The number of stem cells harvested from a biopsy, together with their proliferative capacity, determines a 'multiplicity factor' achieved by a cultured meat production process, thus dictating the reduction in number of animals required to produce a given quantity of meat. This article considers potential scenarios for these critical upstream steps, focusing on the production of cultured beef as an example. Considerations related to donor selection and details of the biopsy process are discussed in detail. The practicalities of various scenarios for cultured beef production, the health of donor animals, and regulatory issues associated with the safety of cultured meat for consumers are also considered. © 2020 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AnimalsBiopsyCattleCell Culture TechniquesFood TechnologyMeatMuscle, SkeletalQuality ControlStem Cellsbiopsycultured beefcultured meatdonor cattleregulatorystem cell isolation

Identifiers

PMID32662148
PMCPMC7689697
OpenAlexW3042306142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.