Evidence map›Paper›PMID 32661928›Full record

ArticleRheumatology international2020

Management of childhood-onset autoinflammatory diseases during the COVID-19 pandemic.

Fatih Haslak, Mehmet Yildiz, Amra Adrovic, Sezgin Sahin, Oya Koker, Ayten Aliyeva, Kenan Barut, Ozgur Kasapcopur

Open access · bronzeAbstract read
In one paragraph

Article in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  6. Severity of SARS-CoV-2 infection in children with inborn errors of immunity (primary immunodeficiencies): a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
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  20. Impact of COVID-19 on Pediatric Immunocompromised Patients.Pediatric clinics of North America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fatih HaslakDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.ORCID 0000-0002-6963-9668
Mehmet YildizDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.ORCID 0000-0002-7834-4909
Amra AdrovicDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.ORCID 0000-0002-2400-6955
Sezgin SahinDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.ORCID 0000-0002-5365-3457
Oya KokerDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.ORCID 0000-0002-0101-9585
Ayten AliyevaDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.
Kenan BarutDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey.ORCID 0000-0001-8459-2872
Ozgur KasapcopurDepartment of Pediatric Rheumatology, Istanbul University-Cerrahpasa Cerrahpasa Medical School, Istanbul, Turkey. ozgurkasapcopur@hotmail.com.ORCID 0000-0002-1125-7720
Istanbul University-Cerrahpaşa · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Concerns regarding the comorbidity as a significant risk factor for Coronavirus Disease-2019 (COVID-19), gave rise to an urgent need for studies evaluating patients with chronic conditions such as autoinflammatory diseases (AIDs). We prepared a web-based survey investigating the clinical findings and contact histories among pediatric patients with AIDs. Confirmed COVID-19 cases, patients with contact history and those with symptoms which were highly suggestive of COVID-19 were called via phone or recruited to a video or face to face appointment. Data of AIDs were obtained from their medical records, retrospectively. Laboratory and screening findings were confirmed by our national health registry website. There were 404 patients (217 female) eligible for the enrollment. During pandemic, 375 (93%) were on colchicine treatment and 48 (11.8%) were receiving biologic treatment. Twenty-four out of 404 patients were admitted to hospital due to COVID-19 suspicion. Severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) was identified through rhinopharyngeal swabs in seven patients, six of whom were only on colchicine treatment. Only one patient with no finding of any severe respiratory complications was hospitalized. All of seven patients recovered completely. Among patients on biologic drugs, neither a symptom nor a positive polymerase chain reaction test for COVID 19 was detected. In conclusion, pediatric patients with AIDs, those receiving biologic treatment and/or colchicine, may not be at increased risk for neither being infected nor the severe disease course.

Indexed as

AdalimumabAdolescentAntibodies, Monoclonal, HumanizedBetacoronavirusBiological ProductsChildChild, PreschoolCohort StudiesColchicineCoronavirus InfectionsCOVID-19Cryopyrin-Associated Periodic SyndromesEtanerceptFamilial Mediterranean FeverFemaleHereditary Autoinflammatory DiseasesAdalimumabAntibodies, Monoclonal, HumanizedBiological ProductscanakinumabColchicineEtanerceptInterleukin 1 Receptor Antagonist ProteintocilizumabTubulin ModulatorsTumor Necrosis Factor InhibitorsAutoinflammatory diseasesBiologic drugColchicineCovid-19SARS-CoV-2

Identifiers

PMID32661928
PMCPMC7355083
OpenAlexW3041176328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.