Evidence map›Paper›PMID 32661815›Full record

ReviewJournal of industrial microbiology & biotechnology2020

Yeast as a promising heterologous host for steroid bioproduction.

Shanhui Xu, Yanran Li

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Metabolic Engineering for Gibberellic Acid Production inMolecules (Basel, Switzerland) · 2026
    Review
  2. Asymmetric Reduction of Unactivated Alkenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Current Trends and Perspectives in Microbial Bioconversions of Steroids.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Article
  12. Review
  13. Recent progress in strategies for steroid production in yeasts.World journal of microbiology & biotechnology · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. A Yeast Chronological Lifespan Assay to Assess Activity of Proteasome Stimulators.Chembiochem : a European journal of chemical biology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shanhui XuDepartment of Chemical and Environmental Engineering, 900 University Avenue, Bourns Hall, Suite A220, Riverside, CA, 92521, USA.
Yanran LiDepartment of Chemical and Environmental Engineering, 900 University Avenue, Bourns Hall, Suite A220, Riverside, CA, 92521, USA. liyanran@engr.ucr.edu.ORCID http://orcid.org/0000-0001-8709-3497
University of California, Riverside · US

Funding

Cancer Research Coordinating Committee CRN-20-634571Directorate for Engineering 1748695
6 · The paper itself

Abstract

With the rapid development of synthetic biology and metabolic engineering technologies, yeast has been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols are essential components of cell membrane, and are the precursors for the biosynthesis of steroid hormones, signaling molecules, and defense molecules in the higher eukaryotes, which are of pharmaceutical and agricultural significance. In this mini-review, we summarize the recent engineering efforts of using yeast to synthesize various steroids, and discuss the structural diversity that the current steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction platform of various steroids from higher eukaryotes.

Indexed as

Metabolic EngineeringSaccharomyces cerevisiaeSterolsSynthetic BiologySterolsBiotransformationDe novo synthesisMetabolic engineeringSteroidsYeast

Identifiers

PMID32661815
PMCPMC7358296
OpenAlexW3042778989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.