SynthesisSurgical endoscopy2020
Perioperative outcomes after laparoscopic cholecystectomy in elderly patients: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06038201 (Cholelithiasis Management), which is not on this map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cholelithiasis Management: Elective Laparoscopic Cholecystectomy vs EUS-guided Gallbladder Cholecystostomy for Gallstones Clearance
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Prophylactic cholecystectomy offers best outcomes following ERCP clearance of common bile duct stones: a meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Ursodeoxycholic acid in the management of symptomatic gallstone disease: systematic review and clinician survey.BJS open · 2023Pooled it
- Patient-reported outcome measures (PROMs) after laparoscopic cholecystectomy: systematic review.BJS open · 2022Pooled it
- Pooled it
- Patient-reported Outcome Measure (PROM) Rand-36-item Health Survey for Gallstone Disease Patients Five Years Following Surgery: A Prospective Randomized Study.In vivo (Athens, Greece)Trial
- Elective endoscopic treatment of benign gallbladder diseases in high-surgical risk patients: a retrospective study.Surgical endoscopy · 2026Article
- United States benign gallbladder disease mortality, 1999-2024: rising cholecystitis and persistent demographic and geographic disparities.Surgical endoscopy · 2026Article
- Artificial intelligence assessment of Parkland's grading scale in laparoscopic cholecystectomy: a step toward real-world outcome prediction.Updates in surgery · 2026Article
- Review
- Association between completion status and perioperative outcomes of laparoscopic cholecystectomy in elderly patients.BMC surgery · 2026Article
- Safety of Cholecystectomy in Nonagenarians: A Systematic Review and Meta-Analysis.Geriatrics (Basel, Switzerland) · 2026Review
- Subtotal cholecystectomy as a bailout strategy in difficult cholecystectomy: Outcomes and patient selection criteria.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Factors associated with conversion from day-case to in-patient elective laparoscopic cholecystectomy surgery across England: an observational study using administrative data.Surgical endoscopy · 2026Observational
- Optimal timing for cholecystectomy following percutaneous cholecystostomy: insights from a multicenter retrospective cohort study.Updates in surgery · 2026Observational
- Acute cholecystitis in older adults with multimorbidity: does surgery offer better outcomes?Hepatobiliary surgery and nutrition · 2025Article
- Is there a difference in textbook outcomes of emergency cholecystectomy in older patients compared with younger patients?World journal of emergency surgery : WJES · 2025Article
- Laparoscopic cholecystectomy in elderly patients: Avoid or expedite? - A comparative cohort study.Journal of minimal access surgery · 2025Article
- Etiological treatment of gallstone acute pancreatitis.World journal of gastrointestinal surgery · 2025Review
- Impact of age on outcomes and hospital costs of urgent laparoscopic cholecystectomy for acute cholecystitis: a retrospective cohort study.BMC surgery · 2025Article
- THE AMERICAN COLLEGE OF SURGEONS-NATIONAL SURGICAL QUALITY IMPROVEMENT PROGRAM CALCULATOR AND SURGICAL APGAR AS PREDICTORS OF POST-CHOLECYSTECTOMY COMPLICATIONS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic cholecystectomy is increasingly performed in an ever ageing population; however, the risks are poorly quantified. The study aims to review the current evidence to quantify further the postoperative risk of cholecystectomy in the elderly population compared to younger patients.
methodA systematic literature search of PubMed, EMBASE and the Cochrane Library databases were conducted including studies reporting laparoscopic cholecystectomy in the elderly population. A meta-analysis was reported in accordance with the recommendations of the Cochrane Library and PRISMA guidelines. Primary outcome was overall complications and secondary outcomes were conversion to open surgery, bile leaks, postoperative mortality and length of stay.
resultsThis review identified 99 studies incorporating 326,517 patients. Increasing age was significantly associated with increased rates of overall complications (OR 2.37, CI
conclusionPostoperative outcomes such as overall and major complications appear to be significantly higher in all age cut-offs in this meta-analysis. This study demonstrated there is a sevenfold increase in perioperative mortality which increases by tenfold in patients > 80 years old. This study appears to confirm preconceived suspicions of higher risks in elderly patients undergoing cholecystectomy and may aid treatment planning and informed consent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.